TOP2

TOP2, as a topoisomerase II, plays a crucial role in DNA replication and transcription. Its complex protein structure endows it with specific catalytic and DNA binding abilities, enabling it to accurately recognize and bind to DNA. During DNA replication, TOP2 ensures the smooth progression of the replication process by solving the "topological problems" caused by topological structure changes. Similarly, during transcription, TOP2 also plays a similar role, ensuring the smooth transcription of RNA polymerase. In addition, the activity of TOP2 is regulated by various factors and signaling molecules, and abnormal regulation can lead to the occurrence of related diseases.

The following TOP2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TOP2 Antibodies

TOP2 Proteins

TOP2 Antibodies

TOP2 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA361947XA01SVG	TOP2 Antibody	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ELISA, WB (ensure identification of antigen)

TOP2 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Species Reactivity	Application
CSB-PA341128XA01DOA	TOP2 Antibody	Arabidopsis thaliana	ELISA, WB (ensure identification of antigen)

TOP2 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA357299XA01SXV	top2 Antibody	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ELISA, WB (ensure identification of antigen)

TOP2 Antibodies for Drosophila melanogaster (Fruit fly)

Code	Product Name	Species Reactivity	Application
CSB-PA322203XA01DLU	Top2 Antibody	Drosophila melanogaster (Fruit fly)	ELISA, WB (ensure identification of antigen)

TOP2 Proteins

TOP2 Proteins for Plasmodium falciparum (isolate K1 / Thailand)

Code	Product Name	Source
CSB-YP340336EWT CSB-EP340336EWT CSB-BP340336EWT CSB-MP340336EWT CSB-EP340336EWT-B	Recombinant Plasmodium falciparum DNA topoisomerase 2 (TOP2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TOP2 Proteins for Candida albicans (Yeast)

Code	Product Name	Source
CSB-YP308937CZF CSB-EP308937CZF CSB-BP308937CZF CSB-MP308937CZF CSB-EP308937CZF-B	Recombinant Candida albicans DNA topoisomerase 2 (TOP2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TOP2 Proteins for BOMMO(Silk moth)

Code	Product Name	Source
CSB-YP521161BTT CSB-EP521161BTT CSB-BP521161BTT CSB-MP521161BTT CSB-EP521161BTT-B	Recombinant Bombyx mori DNA topoisomerase 2 (TOP2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TOP2 Proteins for Crithidia fasciculata

Code	Product Name	Source
CSB-YP335307DXW CSB-EP335307DXW CSB-BP335307DXW CSB-MP335307DXW CSB-EP335307DXW-B	Recombinant DNA topoisomerase 2 (TOP2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TOP2 Proteins for Trypanosoma brucei brucei

Code	Product Name	Source
CSB-YP318979TQV CSB-EP318979TQV CSB-BP318979TQV CSB-MP318979TQV CSB-EP318979TQV-B	Recombinant Trypanosoma brucei brucei DNA topoisomerase 2 (TOP2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TOP2 Proteins for Trypanosoma cruzi

Code	Product Name	Source
CSB-YP339076TQY CSB-EP339076TQY CSB-BP339076TQY CSB-MP339076TQY CSB-EP339076TQY-B	Recombinant DNA topoisomerase 2 (TOP2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TOP2 Proteins for Leishmania chagasi

Code	Product Name	Source
CSB-YP530123LOD CSB-EP530123LOD CSB-BP530123LOD CSB-MP530123LOD CSB-EP530123LOD-B	Recombinant DNA topoisomerase 2 (TOP2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TOP2 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Source
CSB-YP361947SVG CSB-EP361947SVG CSB-BP361947SVG CSB-MP361947SVG CSB-EP361947SVG-B	Recombinant Saccharomyces cerevisiae DNA topoisomerase 2 (TOP2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TOP2 Proteins for Pisum sativum (Garden pea)

Code	Product Name	Source
CSB-YP521299EWE CSB-EP521299EWE CSB-BP521299EWE CSB-MP521299EWE CSB-EP521299EWE-B	Recombinant Pisum sativum DNA topoisomerase 2 (TOP2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TOP2 Proteins for Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)

Code	Product Name	Source
CSB-YP529621CZI CSB-EP529621CZI CSB-BP529621CZI CSB-MP529621CZI CSB-EP529621CZI-B	Recombinant Candida glabrata DNA topoisomerase 2 (TOP2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TOP2 Proteins for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Source
CSB-YP341128DOA CSB-EP341128DOA CSB-BP341128DOA CSB-MP341128DOA CSB-EP341128DOA-B	Recombinant Arabidopsis thaliana DNA topoisomerase 2 (TOP2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TOP2 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Source
CSB-YP357299SXV CSB-EP357299SXV CSB-BP357299SXV CSB-MP357299SXV CSB-EP357299SXV-B	Recombinant Schizosaccharomyces pombe DNA topoisomerase 2 (top2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TOP2 Proteins for Drosophila melanogaster (Fruit fly)

Code	Product Name	Source
CSB-YP322203DLU CSB-EP322203DLU CSB-BP322203DLU CSB-MP322203DLU CSB-EP322203DLU-B	Recombinant Drosophila melanogaster DNA topoisomerase 2 (Top2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TOP2 Proteins for Dictyostelium discoideum (Slime mold)

Code	Product Name	Source
CSB-YP684853DKK CSB-EP684853DKK CSB-BP684853DKK CSB-MP684853DKK CSB-EP684853DKK-B	Recombinant Dictyostelium discoideum Probable DNA topoisomerase 2 (top2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TOP2 Proteins for Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)

Code	Product Name	Source
CSB-YP886149INA CSB-EP886149INA CSB-BP886149INA CSB-MP886149INA CSB-EP886149INA-B	Recombinant Invertebrate iridescent virus 6 DNA topoisomerase 2 (TOP2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TOP2 Proteins for Acanthamoeba polyphaga mimivirus (APMV)

Code	Product Name	Source
CSB-YP726016ADAZ CSB-EP726016ADAZ CSB-BP726016ADAZ CSB-MP726016ADAZ CSB-EP726016ADAZ-B	Recombinant Acanthamoeba polyphaga mimivirus DNA topoisomerase 2 (TOP2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Promotions

Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

Apoptosis mediated by mitochondria The Overview of Hippo Signaling Pathway The Overview of Autophagy Crosstalk Between Autophagy and Apoptosis The Overview of Wnt Signaling Pathway The Overview of Breast Cancer: Related Signaling Pathways, Therapeutic Targets The overview of TGF-β signaling pathway PI3K-Akt Signaling Pathway and Cancer Apoptosis mediated by endoplasmic reticulum Apoptosisi mediated by death receptor Aesthetic Appreciation of Apoptosis Signal Pathway An Overview of Cell Death: Necrosis and Apoptosis Do You Really Know TGF-β Superfamily?Double-Edged Sword: TGF-β The Overview of PI3-Alt Signaling Pathway How to Inquire and Utilize the Signal Pathway on KEGG LPS/TLR4 Signal Transduction Pathway Epigenetic Histone Modifications Pathway What A Paradoxical TNF Signaling Pathway-Based on Different Receptors The Overview of Fc Receptors- Classification, Related Signaling Pathways and Application