IL4

IL4, or Interleukin-4, is a cytokine predominantly secreted by activated T lymphocytes, mast cells, and eosinophils. It exerts its effects by binding to the IL-4R α receptor and subsequently activating the JAK-STAT signaling pathway. This interaction fosters the proliferation and differentiation of Th2 cells while suppressing Th1 cell activity, and it also influences B cell proliferation and antibody class switching. IL-4 is central to orchestrating type 2 immune responses, critically regulating both humoral and adaptive immunity. IL4 is implicated in the immune responses associated with allergic, autoimmune, infectious diseases, and tumors, underscoring its significance in immune system.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of TF-1 cells is 1.864-4.949 ng/mL.

IL4 Recombinant Monoclonal Antibody(CSB-RA240377A0HU)

Validated Data

IHC image of CSB-RA240377A0HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

The following IL4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

IL4 Antibodies

IL4 Proteins

IL4 ELISA Kits

IL4 Antibodies

IL4 Antibodies for Ovis aries (Sheep)

Code	Product Name	Species Reactivity	Application
CSB-PA011659ZA01SH	IL4 Antibody	Ovis aries	ELISA, WB (ensure identification of antigen)

IL4 Antibodies for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Species Reactivity	Application
CSB-PA301281ZA01MOV	IL4 Antibody	Macaca fascicularis	ELISA, WB (ensure identification of antigen)

IL4 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA06737A0Rb	IL4 Antibody	Human	ELISA, IHC
CSB-PA06737B0Rb	IL4 Antibody, HRP conjugated	Human	ELISA
CSB-PA06737C0Rb	IL4 Antibody, FITC conjugated	Human
CSB-PA06737D0Rb	IL4 Antibody, Biotin conjugated	Human	ELISA
CSB-PA556277	IL4 Antibody	Human	ELISA,WB
CSB-PA004908	IL4 Antibody	Human	WB, ELISA
CSB-PA009551	IL4 Antibody	Human	WB, ELISA
CSB-PA009552	IL4 Antibody	Human	WB, ELISA
CSB-PA011659YA01HU	IL4 Antibody	Human, Mouse	ELISA, WB, IHC, IF
CSB-PA011659YB01HU	IL4 Antibody, HRP conjugated	Human	ELISA
CSB-PA011659YC01HU	IL4 Antibody, FITC conjugated	Human
CSB-PA011659YD01HU	IL4 Antibody, Biotin conjugated	Human	ELISA
CSB-RA240377A0HU	IL4 Recombinant Monoclonal Antibody	Human	ELISA, IHC

IL4 Antibodies for Dog

Code	Product Name	Species Reactivity	Application
CSB-PA011659LD01DO	IL4 Antibody, Biotin conjugated	Dog	ELISA
CSB-PA011659LB01DO	IL4 Antibody, HRP conjugated	Dog	ELISA
CSB-PA011659LC01DO	IL4 Antibody, FITC conjugated	Dog
CSB-PA011659LA01DO	IL4 Antibody	Dog	ELISA

IL4 Proteins

IL4 Proteins for Equus caballus (Horse)

Code	Product Name	Source
CSB-YP011659HO CSB-EP011659HO CSB-BP011659HO CSB-MP011659HO CSB-EP011659HO-B	Recombinant Horse Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP011659PI CSB-EP011659PI CSB-BP011659PI CSB-MP011659PI CSB-EP011659PI-B	Recombinant Pig Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus)

Code	Product Name	Source
CSB-YP896421TRF CSB-EP896421TRF CSB-BP896421TRF CSB-MP896421TRF CSB-EP896421TRF-B	Recombinant Tursiops truncatus Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Papio anubis (Olive baboon)

Code	Product Name	Source
CSB-YP768134ERI CSB-EP768134ERI CSB-BP768134ERI CSB-MP768134ERI CSB-EP768134ERI-B	Recombinant Papio anubis Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

Code	Product Name	Source
CSB-YP343994DRI CSB-EP343994DRI CSB-BP343994DRI CSB-MP343994DRI CSB-EP343994DRI-B	Recombinant Cercocebus atys Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Ailuropoda melanoleuca (Giant panda)

Code	Product Name	Source
CSB-YP659536AYX CSB-EP659536AYX CSB-BP659536AYX CSB-MP659536AYX CSB-EP659536AYX-B	Recombinant Ailuropoda melanoleuca Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Felis catus (Cat) (Felis silvestris catus)

Code	Product Name	Source
CSB-YP011659CA CSB-EP011659CA CSB-BP011659CA CSB-MP011659CA CSB-EP011659CA-B	Recombinant Cat Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP301281MOV	Recombinant Macaca fascicularis Interleukin-4 (IL4)	Yeast
CSB-EP301281MOV	Recombinant Macaca fascicularis Interleukin-4 (IL4)	E.coli
CSB-YP301281MOV CSB-EP301281MOV CSB-BP301281MOV CSB-MP301281MOV CSB-EP301281MOV-B	Recombinant Macaca fascicularis Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-MP301281MOV	Recombinant Macaca fascicularis Interleukin-4 (IL4)	Mammalian cell

IL4 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP011659MO CSB-EP011659MO CSB-BP011659MO CSB-MP011659MO CSB-EP011659MO-B	Recombinant Mouse Interleukin-4 (Il4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP003301MO	Recombinant Mouse Interleukin-4 protein (Il4) (Active)	E.coli
CSB-AP004811MO	Recombinant Mouse Interleukin-4 (Il4), partial (Active)	E.coli
CSB-AP004831MO	Recombinant Mouse Interleukin-4 (Il4) (Active)	Mammalian cell

IL4 Proteins for Capra hircus (Goat)

Code	Product Name	Source
CSB-YP011659GO CSB-EP011659GO CSB-BP011659GO CSB-MP011659GO CSB-EP011659GO-B	Recombinant Goat Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Pan troglodytes (Chimpanzee)

Code	Product Name	Source
CSB-YP810227EQV CSB-EP810227EQV CSB-BP810227EQV CSB-MP810227EQV CSB-EP810227EQV-B	Recombinant Pan troglodytes Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Mesocricetus auratus (Golden hamster)

Code	Product Name	Source
CSB-YP713863MRG CSB-EP713863MRG CSB-BP713863MRG CSB-MP713863MRG CSB-EP713863MRG-B	Recombinant Mesocricetus auratus Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP713863MRG	Recombinant Mesocricetus auratus Interleukin-4 (IL4)	Yeast
CSB-EP4841MRG	Recombinant Mesocricetus auratus Interleukin-4 (Il4)	E.coli

IL4 Proteins for Lama glama (Llama)

Code	Product Name	Source
CSB-YP772949LBS CSB-EP772949LBS CSB-BP772949LBS CSB-MP772949LBS CSB-EP772949LBS-B	Recombinant Lama glama Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP772949LBS	Recombinant Lama glama Interleukin-4 (IL4)	E.coli
CSB-YP772949LBS	Recombinant Lama glama Interleukin-4 (IL4)	Yeast
CSB-MP772949LBS	Recombinant Lama glama Interleukin-4 (IL4)	Mammalian cell

IL4 Proteins for Boselaphus tragocamelus (Nilgai)

Code	Product Name	Source
CSB-YP707491BUN CSB-EP707491BUN CSB-BP707491BUN CSB-MP707491BUN CSB-EP707491BUN-B	Recombinant Boselaphus tragocamelus Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Cervus elaphus (Red deer)

Code	Product Name	Source
CSB-YP343955DRN CSB-EP343955DRN CSB-BP343955DRN CSB-MP343955DRN CSB-EP343955DRN-B	Recombinant Cervus elaphus Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP011659HU	Recombinant Human Interleukin-4 (IL4) (Active)	Yeast
CSB-AP001711HU	Recombinant Human Interleukin-4 protein (IL4) (Active)	E.coli
CSB-EP011659HU	Recombinant Human Interleukin-4 (IL-4)	E.coli
CSB-YP011659HU CSB-EP011659HU CSB-BP011659HU CSB-MP011659HU CSB-EP011659HU-B	Recombinant Human Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP011659HUa0	Recombinant Human Interleukin-4 (IL4)	E.coli
CSB-AP004401HU	Recombinant Human Interleukin-4 (IL4) (Active)	E.coli
CSB-AP004511HU	Recombinant Human Interleukin-4 (IL4) (Active)	Mammalian cell
CSB-AP004481HU	Recombinant Human Interleukin-4 (IL4) (Active)	Mammalian cell
CSB-AP005831HU	Recombinant Human Interleukin-4 (IL4), partial (Active) (GMP)	E.Coli
CSB-MP011659HU	Recombinant Human Interleukin-4 (IL4) (Active)	Mammalian cell
CSB-MP011659HUd7-B	Recombinant Human Interleukin-4 (IL4), Biotinylated	Mammalian cell
CSB-MP011659HUd7	Recombinant Human Interleukin-4 (IL4) (Active)	Mammalian cell

IL4 Proteins for Macaca mulatta (Rhesus macaque)

Code	Product Name	Source
CSB-YP011659MOW CSB-EP011659MOW CSB-BP011659MOW CSB-MP011659MOW CSB-EP011659MOW-B	Recombinant Macaca mulatta Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP001991MOW	Recombinant Rhesus Macaque Interleukin-4 protein (IL4) (Active)	E.coli

IL4 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP011659BO CSB-EP011659BO CSB-BP011659BO CSB-MP011659BO CSB-EP011659BO-B	Recombinant Bovine Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP011659BO	Recombinant Bovine Interleukin-4 (IL4)	E.coli
CSB-YP011659BO	Recombinant Bovine Interleukin-4 (IL4)	Bos taurus (Bovine)

IL4 Proteins for Meriones unguiculatus (Mongolian jird) (Mongolian gerbil)

Code	Product Name	Source
CSB-YP343322MRA CSB-EP343322MRA CSB-BP343322MRA CSB-MP343322MRA CSB-EP343322MRA-B	Recombinant Meriones unguiculatus Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Bubalus bubalis (Domestic water buffalo)

Code	Product Name	Source
CSB-YP768743BWX CSB-EP768743BWX CSB-BP768743BWX CSB-MP768743BWX CSB-EP768743BWX-B	Recombinant Bubalus bubalis Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-EP011659DO	Recombinant Dog Interleukin-4 (IL4)	E.coli
CSB-YP011659DO CSB-EP011659DO CSB-BP011659DO CSB-MP011659DO CSB-EP011659DO-B	Recombinant Dog Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Ovis aries (Sheep)

Code	Product Name	Source
CSB-YP011659SH	Recombinant Sheep Interleukin-4 (IL4)	Yeast
CSB-EP011659SH	Recombinant Sheep Interleukin-4 (IL4)	E.coli
CSB-YP011659SH CSB-EP011659SH CSB-BP011659SH CSB-MP011659SH CSB-EP011659SH-B	Recombinant Sheep Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP885625RB CSB-EP885625RB CSB-BP885625RB CSB-MP885625RB CSB-EP885625RB-B	Recombinant Rabbit Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP324000RA CSB-EP324000RA CSB-BP324000RA CSB-MP324000RA CSB-EP324000RA-B	Recombinant Rat Interleukin-4 (Il4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 Proteins for Bubalus carabanensis (Swamp type water buffalo) (Bubalus bubalis carabanensis)

Code	Product Name	Source
CSB-YP649260BAAW CSB-EP649260BAAW CSB-BP649260BAAW CSB-MP649260BAAW CSB-EP649260BAAW-B	Recombinant Bubalus carabanensis Interleukin-4 (IL4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL4 ELISA Kit

IL4 ELISA Kit for Mesocricetus auratus (Golden hamster)

Code	Product Name	Sample Types	Sensitivity
CSB-EL011659HA	Hamster Interleukin-4(IL4) ELISA kit	serum, plasma, tissue homogenates	2.34 pg/mL

IL4 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Sample Types	Sensitivity
CSB-E11259c	Dog interleukin 4,IL-4 ELISA Kit	serum, plasma, tissue homogenates	1.56 pg/mL

IL4 ELISA Kit for Ovis aries (Sheep)

Code	Product Name	Sample Types	Sensitivity
CSB-E15963Sh	Sheep Interleukin 4(IL-4)ELISA Kit	serum, plasma, tissue homogenates	1.56 pg/mL

IL4 ELISA Kit for Rattus norvegicus (Rat)

Code	Product Name	Sample Types	Sensitivity
CSB-E04635r	Rat Interleukin 4,IL-4 ELISA KIT	serum, plasma, tissue homogenates	3.9 pg/mL

IL4 ELISA Kit for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Sample Types	Sensitivity
CSB-E06902Rb	Rabbit Interleukin 4,IL-4 ELISA Kit	serum, plasma, tissue homogenates	0.156 pg/mL

IL4 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E04633h	Human Interleukin 4,IL-4 ELISA KIT	serum, plasma, tissue homogenates.	7.8 pg/ml

IL4 ELISA Kit for Sus scrofa (Pig)

Code	Product Name	Sample Types	Sensitivity
CSB-E06785p	Pig interleukin 4,IL-4 ELISA Kit	serum, plasma, cell culture supernates, tissue homogenates	1.56 pg/mL

IL4 ELISA Kit for Bos taurus (Bovine)

Code	Product Name	Sample Types	Sensitivity
CSB-E12898B	Bovine interleukin 4,IL-4 ELISA Kit	serum, plasma, tissue homogenates	3.12 pg/mL

IL4 ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-E04634m	Mouse Interleukin 4,IL-4 ELISA KIT	serum, plasma, tissue homogenates	7.8 pg/ml

IL4 ELISA Kit for Capra hircus (Goat)

Code	Product Name	Sample Types	Sensitivity
CSB-E09808g	Goat Interleukin 4,IL-4 ELISA Kit	serum, plasma, tissue homogenates	3.9 pg/mL

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