IL4 Antibody

Code: CSB-PA011659ZA01SH

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Size:

0.1ml

0.1ml1ml

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Species Reactivity: Ovis aries

Raised in: Rabbit

Application: ELISA, WB (ensure identification of antigen)

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Target Background

Product Details

Uniprot NO.

P30368

Target Names

IL4

Alternative Names

IL4 antibody; IL-4Interleukin-4 antibody; IL-4 antibody; B-cell stimulatory factor 1 antibody; BSF-1 antibody; Lymphocyte stimulatory factor 1 antibody

Raised in

Rabbit

Species Reactivity

Ovis aries

Immunogen

Recombinant Ovis aries IL4 protein

Immunogen Species

Ovis aries (Sheep)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB (ensure identification of antigen)

Lead Time

Made-to-order (12-14 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

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Target Background

Function(From Uniprot)

Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.

Gene References into Functions

Local production of the prototypic immunomodulatory cytokine IL-4 in transplanted corneal endothelium induces eosinophilia, inflammation, and rejection. PMID:16081789
Early IL-4 gene expression in abomasum is associated with resistance to Haemonchus infection. PMID:27059919

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Subcellular Location

Secreted.

Protein Families

IL-4/IL-13 family

Database Links

UNIGENE: Oar.377

KEGG: oas:443327

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