LY6G6D (US20240190966A1 Biosimilar) Recombinant Monoclonal Antibody

Code: CSB-RA013246MB1HU
Size:
100ug
100ug500ug1mg5mg10mg50mg100mg200mg
US$199
Quantity:
Species Reactivity: Human
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Product Details

Uniprot NO.
Alternative Names
Lymphocyte antigen 6 complex locus protein G6d; Protein Ly6-D; Megakaryocyte-enhanced gene transcript 1 protein; LY6G6D; C6orf23; G6D; MEGT1; NG25
Species Reactivity
Human
Immunogen
Recombinant Human LY6G6D protein
Conjugate
Non-conjugated
Clonality
Monoclonal
Buffer
0.01M PBS,pH7.4
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Notes
Validation Status
Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
Guaranteed Quality
① Antibody purity > 95% tested by SDS-PAGE.
② Endotoxin level < 0.1EU/ug tested by LAL method.
Lead Time
In stock
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Concentration
It differs from different batches. Please contact us to confirm it.
Usage
It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.
Datasheet & COA
Description

This recombinant monoclonal antibody targets LY6G6D (Lymphocyte Antigen 6 Family Member G6D), a glycosylphosphatidylinositol-anchored cell surface protein belonging to the LY6/uPAR superfamily. LY6G6D is predominantly expressed in immune cells and has been implicated in immune regulation and cell signaling processes. This protein shows differential expression patterns in various immunological contexts and has garnered research interest for its potential roles in inflammatory responses and immune cell modulation. Aberrant expression of LY6G6D has been associated with autoimmune conditions and certain hematological disorders, making it a relevant target for immunological research.

Developed as a research-grade biosimilar to the reference antibody described in patent US20240190966A1, this antibody provides researchers with a reliable tool for investigating LY6G6D biology and function. It enables studies exploring the protein's role in immune cell behavior, signal transduction pathways, and disease mechanisms. This antibody serves as a valuable reagent for advancing understanding of LY6 family proteins in health and disease contexts.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Gene References into Functions
  1. Frequencies of the DRB1, DQA1, DQB1 and TNFA alleles in immigrant population of West Siberia PMID:19807019

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Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor. Cell projection, filopodium.
Tissue Specificity
Expressed in the adult lung, and in fetal liver, lung, kidney, brain and spleen.
Database Links

HGNC: 13935

UNIGENE: Hs.591792

KEGG: hsa:58530

STRING: 9606.ENSP00000364985

OMIM: 606038

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