LY6G6D Recombinant Monoclonal Antibody

LY6G6D, also known as lymphocyte antigen 6 complex locus protein G6d, is a GPI-anchored cell surface protein belonging to the Ly6 family. This target has garnered significant attention in immunology research due to its restricted expression pattern and potential role in immune cell function. Located within the major histocompatibility complex class III region on chromosome 6, LY6G6D represents an intriguing molecule for researchers investigating immune regulation and cell surface marker biology.

This recombinant monoclonal antibody, clone 8I8, offers the reproducibility and consistency that demanding experimental workflows require. Because it is produced using recombinant technology with a defined sequence, you can expect reliable performance across experiments and between lots, eliminating the variability often encountered with traditional hybridoma-derived antibodies. The human IgG1 isotype format and affinity-chromatography purification ensure high purity suitable for sensitive detection methods.

Functional ELISA validation demonstrates exceptional binding affinity, with EC50 values in the low nanogram per milliliter range for both human LY6G6D and Macaca fascicularis LY6G6D proteins, confirming robust cross-species reactivity that expands your experimental options across primate models. Flow cytometry validation using LY6G6D-transfected HEK293T stable cells shows clear discrimination between transfected and untransfected populations, confirming specificity for cell surface detection applications.

The unconjugated format provides flexibility for pairing with your preferred secondary detection systems across ELISA and flow cytometry platforms. Whether you are characterizing immune cell populations, investigating Ly6 family protein biology, or developing detection assays requiring primate cross-species reactivity, this antibody delivers the performance and consistency your immunology research demands.