FAS

FAS, tumor necrosis factor receptor superfamily member 6, alias APO-1, CD95, TNFRSF6, is a cell surface death receptor belonging to the tumor necrosis factor receptor superfamily. FAS is mainly expressed on the surface of cells of various tissues, and a small amount exists in plasma in a soluble form.
The mechanism of action of FAS is to form a death-inducing signaling complex (DISC) by binding to its ligand, FasL, which in turn activates the downstream caspase apoptosis cascade and causes apoptosis. FAS plays an important role in the immune system, especially in apoptosis, immune tolerance and anti-tumor immune response. Aberrant activation or inhibition of the FAS signaling pathway has been associated with a variety of diseases, including autoimmune diseases, certain types of cancer, and immunodeficiency diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

FASN Recombinant Monoclonal Antibody(CSB-RA240595A0HU)

Validated Data

Immunofluorescence staining of Hela Cells with CSB-RA240595A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

Overlay histogram showing A549 cells stained with CSB-RA240595A0HU (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then incubated in 10% normal goat serum to block non-specific protein-protein interactions followedby the antibody (1µg/1*10⁶ cells) for 1 h at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1µg/1*10⁶ cells) used under the same conditions. Acquisition of >10,000 events was performed.

Human Fatty acid synthase(FASN) ELISA kit(CSB-EL008435HU)

Validated Data

Code: CSB-EL008435HU

Size: 96T,5×96T,10×96T

Sensitivity: 0.39 ng/mL

Detection Range: 1.56 ng/mL-100 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following FAS reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

FAS Antibodies

FAS Proteins

FAS ELISA Kits

FAS Antibodies

FAS Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA06354A0Rb	FAS Antibody	Human	ELISA, IHC, IF
CSB-PA146193	FAS Antibody	Human	ELISA,WB
CSB-PA942791	FAS Antibody	Human	ELISA,WB,IHC
CSB-PA001488	FAS Antibody	Human	WB, IHC, ELISA
CSB-PA002481	FAS Antibody	Human	WB, IF, ELISA
CSB-PA006041	FAS Antibody	Human	WB, ELISA
CSB-PA009527	Phospho-FAS (Y291) Antibody	Human	IF, ELISA
CSB-PA185779	FAS Antibody	Human	ELISA,WB,IHC
CSB-RA252392A0HU	FAS Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC

FAS Antibodies for Zebrafish

Code	Product Name	Species Reactivity	Application
CSB-PA24199A0Rb	fas Antibody	Zebrafish	ELISA, WB
CSB-PA24199B0Rb	fas Antibody, HRP conjugated	Zebrafish	ELISA
CSB-PA24199C0Rb	fas Antibody, FITC conjugated	Zebrafish
CSB-PA24199D0Rb	fas Antibody, Biotin conjugated	Zebrafish	ELISA

FAS Proteins

FAS Proteins for Macaca nemestrina (Pig-tailed macaque)

Code	Product Name	Source
CSB-YP857720MOX CSB-EP857720MOX CSB-BP857720MOX CSB-MP857720MOX CSB-EP857720MOX-B	Recombinant Macaca nemestrina Tumor necrosis factor receptor superfamily member 6 (FAS), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FAS Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP890581MOV CSB-EP890581MOV CSB-BP890581MOV CSB-MP890581MOV CSB-EP890581MOV-B	Recombinant Macaca fascicularis Tumor necrosis factor receptor superfamily member 6 (FAS), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FAS Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP737175RA CSB-EP737175RA CSB-BP737175RA CSB-MP737175RA CSB-EP737175RA-B	Recombinant Rat Tumor necrosis factor receptor superfamily member 6 (Fas), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FAS Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP008433HU CSB-EP008433HU CSB-BP008433HU CSB-MP008433HU CSB-EP008433HU-B	Recombinant Human Tumor necrosis factor receptor superfamily member 6 (FAS), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP002311HU	Recombinant Human Tumor necrosis factor receptor superfamily member 6 protein (FAS), partial (Active)	E.coli
CSB-CF008433HU(A4)	Recombinant Human Tumor necrosis factor receptor superfamily member 6 (FAS)	in vitro E.coli expression system
CSB-MP008433HU(A4)	Recombinant Human Tumor necrosis factor receptor superfamily member 6 (FAS)-VLPs	Mammalian cell
CSB-MP008433HU	Recombinant Human Tumor necrosis factor receptor superfamily member 6 (FAS), partial	Mammalian cell

FAS Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-CF008433PI	Recombinant Pig Tumor necrosis factor receptor superfamily member 6 (FAS)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP008433PI1 CSB-EP008433PI1 CSB-BP008433PI1 CSB-MP008433PI1 CSB-EP008433PI1-B	Recombinant Pig Tumor necrosis factor receptor superfamily member 6 (FAS), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FAS Proteins for Macaca mulatta (Rhesus macaque)

Code	Product Name	Source
CSB-YP859783MOW CSB-EP859783MOW CSB-BP859783MOW CSB-MP859783MOW CSB-EP859783MOW-B	Recombinant Macaca mulatta Tumor necrosis factor receptor superfamily member 6 (FAS), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FAS Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-CF008433BO	Recombinant Bovine Tumor necrosis factor receptor superfamily member 6 (FAS)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP008433BO1 CSB-EP008433BO1 CSB-BP008433BO1 CSB-MP008433BO1 CSB-EP008433BO1-B	Recombinant Bovine Tumor necrosis factor receptor superfamily member 6 (FAS), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FAS Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-CF008433MO	Recombinant Mouse Tumor necrosis factor receptor superfamily member 6 (Fas)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP008433MO1 CSB-EP008433MO1 CSB-BP008433MO1 CSB-MP008433MO1 CSB-EP008433MO1-B	Recombinant Mouse Tumor necrosis factor receptor superfamily member 6 (Fas), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FAS Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

Code	Product Name	Source
CSB-YP861037DRI CSB-EP861037DRI CSB-BP861037DRI CSB-MP861037DRI CSB-EP861037DRI-B	Recombinant Cercocebus atys Tumor necrosis factor receptor superfamily member 6 (FAS), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli