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Recombinant Macaca fascicularis Tumor necrosis factor receptor superfamily member 6 (FAS), partial

Code
MSDS
MSDS Datasheet
Size Pls inquire
Source
Conjugate
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Product Details

Abbreviation
FAS
Purity
>85% (SDS-PAGE)
Target Names
FAS
Uniprot NO.
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Source
Yeast
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
Subcellular Location
Cell membrane; Single-pass type I membrane protein. Membrane raft.
Database Links

UNIGENE: Mfa.5418

KEGG: mcf:102140989

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Related pathways
MAPK signaling pathwayp53 signaling pathwayNatural killer cell mediated cytotoxicityTNF signaling pathwayApoptosisNecroptosis
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