KRT15 Antibody

CSB-PA591463
Size:
50μl
50μl100μl
US$166
Quantity:
Species Reactivity: Human,Mouse,Rat
Raised in: Rabbit
Application: ELISA,WB
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Product Details

Uniprot NO.
Target Names
KRT15
Alternative Names
AI528832 antibody; CK 15 antibody; CK-15 antibody; CK15 antibody; Cytokeratin-15 antibody; Cytokeratin15 antibody; K15 antibody; K1C15_HUMAN antibody; K1CO antibody; Ka15 antibody; Keratin 15 antibody; Keratin 15 basic antibody; Keratin 15 beta antibody; Keratin antibody; Keratin complex 1 acidic gene 15 antibody; Keratin type I cytoskeletal 15 antibody; Keratin-15 antibody; Keratin15 antibody; KRT 15 antibody; Krt1-15 antibody; KRT15 antibody; KRTB antibody; KRTL15 antibody; Type I cytoskeletal 15 antibody; Type I keratin Ka15 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Fusion protein of Human KRT15
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Tested Applications
ELISA,WB
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA
Images
  • Gel: 10%SDS-PAGE, Lysate: 24 μg, Lane: Human ovarian cancer tissue, Primary antibody: CSB-PA591463(KRT15 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
Description

Customer Reviews and Q&A

 Customer Reviews

Target Background

Gene References into Functions
  1. Underexpression of CK15 is associated with Esophageal Squamous Cell Carcinomas. PMID:27797221
  2. Cytokeratin 15 is upregulated in a subset of urothelial cell carcinomas. PMID:24260555
  3. K15 is expressed variably in both oral squamous cell carcinoma and squamous intraepithelial neoplasm PMID:22648550
  4. both expanded limbal NCs and HUVEC rejoined with LEPC to form spheres to upregulate expression of DeltaNp63alpha, CK15, and CEBPdelta, the former but not the latter abolished expression of CK12 keratin. PMID:22538425
  5. Stromal expression of KRT15, TCN1, and HOXB13 was significantly correlated with tumor grade, stromal hypercellularity, mitotic activity and microscopic borders. PMID:21574054
  6. CK15 highlights BZ cells in normal human follicles PMID:21251039
  7. Physiological concentrations of thyroid hormones T3 and T4 enhance keratin 15 promoter activity and expression in epithelial stem cells of adult human scalp hair follicles in situ and in vitro. PMID:20656376
  8. Report expression of stem-cell markers cytokeratin 15 and nestin in primary adnexal neoplasms. PMID:20700038
  9. Results identify the regulators of keratin 15 promoter activity and their binding sites. PMID:15060141
  10. Cytokeratin 15 expression pattern is useful in terms of distinguishing trichoepithelioma from basal cell carcinoma. PMID:18789069
  11. marker of the hair follicle stem cells; diminished during scarring in alopecia and discoid lupus erythematosus PMID:19162247
  12. Identification of a subset of breast carcinomas characterized by expression of CK15: relationship between CK15+ progenitor/amplified cells and pre-malignant lesions and invasive disease is reported. PMID:19383306
  13. KRT15 is a Gli1-responsive gene in human skin keratinocytes PMID:20050020
  14. KRT15 mRNA is selectively expressed in human hair follicle stem cells, while KRT15 protein is not. PMID:20050020

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Protein Families
Intermediate filament family
Tissue Specificity
Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Exp
Database Links

HGNC: 6421

UNIGENE: Hs.654570

KEGG: hsa:3866

STRING: 9606.ENSP00000254043

OMIM: 148030

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