CHRM3

CHRM3, the muscarinic acetylcholine receptor 3, is a G protein-coupled receptor encoded by the CHRM3 gene and expressed in smooth muscle, heart, and secretory glands. It activates Gq/11 protein upon acetylcholine binding, promoting phosphatidylinositol 4,5-bisphosphate conversion to inositol triphosphate and diacylglycerol, causing intracellular calcium release and protein kinase C activation. CHRM3 regulates gastrointestinal peristalsis, glandular secretion, cardiac rhythm, and vasodilation, and is implicated in conditions like asthma and cardiovascular disease.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CHRM3 Recombinant Monoclonal Antibody(CSB-RA827961A0HU)

Validated Data

IHC image of CSB-RA827961A0HU diluted at 1:300 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody

IHC image of CSB-RA827961A0HU diluted at 1:300 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody

The following CHRM3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CHRM3 Antibodies

CHRM3 Proteins

CHRM3 Antibodies

CHRM3 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA005383ESR2HU	CHRM3 Antibody	Human	ELISA, WB, IHC
CSB-PA005383ESR1HU	CHRM3 Antibody	Human	ELISA
CSB-PA005383LA01HU	CHRM3 Antibody	Human	ELISA, IHC, IF
CSB-PA005383LB01HU	CHRM3 Antibody, HRP conjugated	Human	ELISA
CSB-PA005383LC01HU	CHRM3 Antibody, FITC conjugated	Human
CSB-RA827961A0HU	CHRM3 Recombinant Monoclonal Antibody	Human	ELISA, IHC

CHRM3 Proteins

CHRM3 Proteins for Pan troglodytes (Chimpanzee)

Code	Product Name	Source
CSB-CF882017EQV	Recombinant Pan troglodytes Muscarinic acetylcholine receptor M3 (CHRM3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP882017EQV1 CSB-EP882017EQV1 CSB-BP882017EQV1 CSB-MP882017EQV1 CSB-EP882017EQV1-B	Recombinant Pan troglodytes Muscarinic acetylcholine receptor M3 (CHRM3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHRM3 Proteins for Pongo pygmaeus (Bornean orangutan)

Code	Product Name	Source
CSB-CF873566EXP	Recombinant Pongo pygmaeus Muscarinic acetylcholine receptor M3 (CHRM3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP873566EXP1 CSB-EP873566EXP1 CSB-BP873566EXP1 CSB-MP873566EXP1 CSB-EP873566EXP1-B	Recombinant Pongo pygmaeus Muscarinic acetylcholine receptor M3 (CHRM3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHRM3 Proteins for Gorilla gorilla gorilla (Western lowland gorilla)

Code	Product Name	Source
CSB-CF865050GGZ	Recombinant Gorilla gorilla gorilla Muscarinic acetylcholine receptor M3 (CHRM3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP865050GGZ1 CSB-EP865050GGZ1 CSB-BP865050GGZ1 CSB-MP865050GGZ1 CSB-EP865050GGZ1-B	Recombinant Gorilla gorilla gorilla Muscarinic acetylcholine receptor M3 (CHRM3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHRM3 Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-CF005383CH	Recombinant Chicken Muscarinic acetylcholine receptor M3 (CHRM3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP005383CH1 CSB-EP005383CH1 CSB-BP005383CH1 CSB-MP005383CH1 CSB-EP005383CH1-B	Recombinant Chicken Muscarinic acetylcholine receptor M3 (CHRM3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHRM3 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-CF005383RA	Recombinant Rat Muscarinic acetylcholine receptor M3 (Chrm3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP005383RA1 CSB-EP005383RA1 CSB-BP005383RA1 CSB-MP005383RA1 CSB-EP005383RA1-B	Recombinant Rat Muscarinic acetylcholine receptor M3 (Chrm3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHRM3 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP005383HU	Recombinant Human Muscarinic acetylcholine receptor M3 (CHRM3), partial	Yeast
CSB-EP005383HU	Recombinant Human Muscarinic acetylcholine receptor M3 (CHRM3), partial	E.coli
CSB-YP005383HU CSB-EP005383HU CSB-BP005383HU CSB-MP005383HU CSB-EP005383HU-B	Recombinant Human Muscarinic acetylcholine receptor M3 (CHRM3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP005383HUb0	Recombinant Human Muscarinic acetylcholine receptor M3 (CHRM3), partial	E.coli

CHRM3 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-CF005383PI	Recombinant Pig Muscarinic acetylcholine receptor M3 (CHRM3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP005383PI1 CSB-EP005383PI1 CSB-BP005383PI1 CSB-MP005383PI1 CSB-EP005383PI1-B	Recombinant Pig Muscarinic acetylcholine receptor M3 (CHRM3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHRM3 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-CF005383BO	Recombinant Bovine Muscarinic acetylcholine receptor M3 (CHRM3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP005383BO1 CSB-EP005383BO1 CSB-BP005383BO1 CSB-MP005383BO1 CSB-EP005383BO1-B	Recombinant Bovine Muscarinic acetylcholine receptor M3 (CHRM3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CHRM3 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-CF872136MO	Recombinant Mouse Muscarinic acetylcholine receptor M3 (Chrm3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP872136MO1 CSB-EP872136MO1 CSB-BP872136MO1 CSB-MP872136MO1 CSB-EP872136MO1-B	Recombinant Mouse Muscarinic acetylcholine receptor M3 (Chrm3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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CHRM3

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