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Recombinant Human Probable G-protein coupled receptor 85 (GPR85)

Recombinant Human Probable G-protein coupled receptor 85 (GPR85)

Code: CSB-CF009837HU

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Size:

20μg100μg

US$5263

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Express system: in vitro E.coli expression system

Species: Homo sapiens (Human)

Tag Info: N-terminal 10xHis-tagged

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Target Background

Product Details

Target Names

GPR85

Uniprot NO.

P60893

Species

Homo sapiens (Human)

Source

in vitro E.coli expression system

Expression Region

1-370

Target Protein Sequence

MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL DLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRY LAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFR ANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAA ANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGP YLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKS RLPREPYCVI
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full length protein

Tag Info

N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

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Target Background

Function(From Uniprot)

Orphan receptor.

Gene References into Functions

Risk-associated variants in GPR85 are associated with phenotypes similar to those found in patients with schizophrenia. PMID:22968816
The areas expressing high levels of SREB2 mRNA overlap with brain structures known to possess high levels of plasticity, namely, the hippocampal formation, olfactory system, and supraoptic and paraventricular nuclei. PMID:15893849
Theses data implicate SREB2 as a potential risk factor for psychiatric disorders. PMID:18413613

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Subcellular Location

Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum.

Protein Families

G-protein coupled receptor 1 family

Tissue Specificity

Highly expressed in brain and testis. Lower levels in small intestine, placenta and spleen. In brain regions, detected in all regions tested, but somewhat lower levels in the corpus callosum, medulla and spinal cord.

Database Links

HGNC: 4536

UNIGENE: Hs.152009

KEGG: hsa:54329

STRING: 9606.ENSP00000297146

OMIM: 605188

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