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Recombinant Human Probable G-protein coupled receptor 85 (GPR85), partial

Recombinant Human Probable G-protein coupled receptor 85 (GPR85), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

GPR85

Uniprot NO.

P60893

Alternative Names

GPR85; SREB2; Probable G-protein coupled receptor 85; Super conserved receptor expressed in brain 2

Species

Homo sapiens (Human)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Orphan receptor.

Gene References into Functions

Risk-associated variants in GPR85 are associated with phenotypes similar to those found in patients with schizophrenia. PMID:22968816
The areas expressing high levels of SREB2 mRNA overlap with brain structures known to possess high levels of plasticity, namely, the hippocampal formation, olfactory system, and supraoptic and paraventricular nuclei. PMID:15893849
Theses data implicate SREB2 as a potential risk factor for psychiatric disorders. PMID:18413613

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Subcellular Location

Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum.

Protein Families

G-protein coupled receptor 1 family

Tissue Specificity

Highly expressed in brain and testis. Lower levels in small intestine, placenta and spleen. In brain regions, detected in all regions tested, but somewhat lower levels in the corpus callosum, medulla and spinal cord.

Database Links

HGNC: 4536

UNIGENE: Hs.152009

KEGG: hsa:54329

STRING: 9606.ENSP00000297146

OMIM: 605188

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