GPR85 Antibody

CSB-PA030117

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Size:

50μg100μg

US$119

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Species Reactivity: Human,Mouse,Rat

Raised in: Rabbit

Application: IHC, IF, ELISA

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Target Background

Product Details

Uniprot NO.

P60893

Target Names

GPR85

Alternative Names

GPR85; SREB2; Probable G-protein coupled receptor 85; Super conserved receptor expressed in brain 2

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from the Internal region of Human GPR85.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Tested Applications

IHC, IF, ELISA

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Protocols

Immunohistochemistry (IHC) Protocol Immunofluorescence (IF) Protocol ELISA Protocol

Datasheet & COA

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Description

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Target Background

Function

Orphan receptor.

Gene References into Functions

Risk-associated variants in GPR85 are associated with phenotypes similar to those found in patients with schizophrenia. PMID:22968816
The areas expressing high levels of SREB2 mRNA overlap with brain structures known to possess high levels of plasticity, namely, the hippocampal formation, olfactory system, and supraoptic and paraventricular nuclei. PMID:15893849
Theses data implicate SREB2 as a potential risk factor for psychiatric disorders. PMID:18413613

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Subcellular Location

Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum.

Protein Families

G-protein coupled receptor 1 family

Tissue Specificity

Highly expressed in brain and testis. Lower levels in small intestine, placenta and spleen. In brain regions, detected in all regions tested, but somewhat lower levels in the corpus callosum, medulla and spinal cord.

Database Links

HGNC: 4536

UNIGENE: Hs.152009

KEGG: hsa:54329

STRING: 9606.ENSP00000297146

OMIM: 605188

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