Recombinant Mouse C-C motif chemokine 9 (Ccl9)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Ccl9

Uniprot NO.

P51670

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

22-122

Target Protein Sequence

QITHATETK EVQSSLKAQQ GLEIEMFHMG FQDSSDCCLS YNSRIQCSRF IGYFPTSGGC TRPGIIFISK RGFQVCANPS DRRVQRCIER LEQNSQPRTY KQ
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Monokine with inflammatory, pyrogenic and chemokinetic properties. Circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors.

Gene References into Functions

CCL9 secreted by splenic macrophages induces a CCR1dependent accumulation of MDSCs. PMID:30365155
Results show that MIP-1g promotes tumor cell growth in vitro through the activation of NFkB pathway in colorectal tumor cells. PMID:28108624
we report that chemokine CCL9 was highly induced in Gr-1(+)CD11b(+) immature myeloid cells and in premetastatic lung in tumor-bearing mice PMID:26483204
Plasmid codelivery of murine CCL19 and CCL28 enhanced Ag-specific systemic and mucosal Ab responses to HIV-1 gp140, augmented balanced Th1/Th2 responses, and increased lymphocyte subsets in various lymphoid tissues. PMID:23858028
There is protein-DNA interaction between ETV5 and Ccl9, suggesting that ETV5 might be a direct regulator of Ccl9 expression. PMID:20799334
Results reveal the potential involvement of CCL9 and CCR1 in macrophage and microglial cells by CpG-ODNs and may help understanding the role of the chemokine/chemokine receptor pairs in macrophage/microglia under physiologic and pathologic conditions. PMID:19883904
MRP-2 may be an important contributing factor in the development of atherosclerosis PMID:12173416
CCL9 and its receptor CCR1 are the major chemokine and receptor species expressed by osteoclasts, CCL9 has a role in the regulation of bone resorption PMID:12397598
An important role for CCL9 is demonstrated in the recruitment of CD11b+ dendritic cells to the dome regions of mouse Peyer's patches. PMID:12960300
MIP-1 gamma plays an important role in the differentiation & survival of osteoclasts, & bone resorption, most likely via an autocrine pathway. PMID:15265944
Keratinocyte-derived chemokine (KC) and MIP-2 alpha differ in their mediation of neutrophil function (apoptosis and chemotaxis) and contribution to the pathogenesis of lung injury following hemorrhage subsequent to sepsis. PMID:15961314
BCR/ABL repressed CCL9 expression at the transcriptional level PMID:17160016
involved in calcium mobilization and chemotaxis PMID:11500837