Ccl9 Antibody

Code: CSB-PA09119A0Rb
Size:
20μg
20μg50μg100μg
US$83
Quantity:
Species Reactivity: Mouse
Raised in: Rabbit
Application: ELISA
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Product Details

Uniprot NO.
Target Names
Ccl9
Alternative Names
CCF18 antibody; Ccl9 antibody; CCL9(31-101) antibody; CCL9_MOUSE antibody; Chemokine CC motif ligand 9 antibody; Macrophage inflammatory protein 1-gamma antibody; Macrophage inflammatory protein-related protein 2 antibody; MIP-1-gamma antibody; MRP-2 antibody; SCYA10 antibody; SCYA9 antibody; Small inducible cytokine A9 antibody; Small-inducible cytokine A9 antibody
Raised in
Rabbit
Species Reactivity
Mouse
Immunogen
Recombinant Mouse C-C motif chemokine 9 protein (22-114AA)
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.1mol/L NaCl, 15mmol/L NaN3, PH7.2
Tested Applications
ELISA
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Monokine with inflammatory, pyrogenic and chemokinetic properties. Circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors.
Gene References into Functions
  1. CCL9 secreted by splenic macrophages induces a CCR1dependent accumulation of MDSCs. PMID:30365155
  2. Results show that MIP-1g promotes tumor cell growth in vitro through the activation of NFkB pathway in colorectal tumor cells. PMID:28108624
  3. we report that chemokine CCL9 was highly induced in Gr-1(+)CD11b(+) immature myeloid cells and in premetastatic lung in tumor-bearing mice PMID:26483204
  4. Plasmid codelivery of murine CCL19 and CCL28 enhanced Ag-specific systemic and mucosal Ab responses to HIV-1 gp140, augmented balanced Th1/Th2 responses, and increased lymphocyte subsets in various lymphoid tissues. PMID:23858028
  5. There is protein-DNA interaction between ETV5 and Ccl9, suggesting that ETV5 might be a direct regulator of Ccl9 expression. PMID:20799334
  6. Results reveal the potential involvement of CCL9 and CCR1 in macrophage and microglial cells by CpG-ODNs and may help understanding the role of the chemokine/chemokine receptor pairs in macrophage/microglia under physiologic and pathologic conditions. PMID:19883904
  7. MRP-2 may be an important contributing factor in the development of atherosclerosis PMID:12173416
  8. CCL9 and its receptor CCR1 are the major chemokine and receptor species expressed by osteoclasts, CCL9 has a role in the regulation of bone resorption PMID:12397598
  9. An important role for CCL9 is demonstrated in the recruitment of CD11b+ dendritic cells to the dome regions of mouse Peyer's patches. PMID:12960300
  10. MIP-1 gamma plays an important role in the differentiation & survival of osteoclasts, & bone resorption, most likely via an autocrine pathway. PMID:15265944
  11. Keratinocyte-derived chemokine (KC) and MIP-2 alpha differ in their mediation of neutrophil function (apoptosis and chemotaxis) and contribution to the pathogenesis of lung injury following hemorrhage subsequent to sepsis. PMID:15961314
  12. BCR/ABL repressed CCL9 expression at the transcriptional level PMID:17160016
  13. involved in calcium mobilization and chemotaxis PMID:11500837

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Subcellular Location
Secreted.
Protein Families
Intercrine beta (chemokine CC) family
Tissue Specificity
Expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain.
Database Links
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No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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