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Recombinant Arabidopsis thaliana Mitochondrial outer membrane protein porin 1 (VDAC1)

Recombinant Arabidopsis thaliana Mitochondrial outer membrane protein porin 1 (VDAC1)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

VDAC1

Purity

>85% (SDS-PAGE)

Target Names

VDAC1

Uniprot NO.

Q9SRH5

Species

Arabidopsis thaliana (Mouse-ear cress)

Source

Yeast

Expression Region

2-276

Target Protein Sequence

VKGPGLYTE IGKKARDLLY KDHNSDQKFS ITTFSPAGVA ITSTGTKKGD LLLGDVAFQS RRKNITTDLK VCTDSTFLIT ATVDEAAPGL RSIFSFKVPD QNSGKVELQY LHEYAGISTS MGLTQNPTVN FSGVIGSNVL AVGTDVSFDT KSGNFTKINA GLSFTKEDLI ASLTVNDKGD LLNASYYHIV NPLFNTAVGA EVSHKLSSKD STITVGTQHS LDPLTSVKAR VNSAGIASAL IQHEWKPKSF FTISGEVDTK SIDKSAKVGL ALALKP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. Involved in plant development at reproductive stage, is important for pollen development and may regulate hydrogen peroxide generation during disease resistance.

Gene References into Functions

Abnormal ovules in the process of female gametogenesis were observed. Both mitochondrial transmembrane potential and ATP synthesis rate were obviously reduced in the mitochondria isolated from atvdac1 plants. PMID:25192453
Data indicate that both voltage-dependent anion channel 1 (AtVDAC1) and calcium sensor CBL1 regulate cold stress responses during seed germination and plant development. PMID:23344040
AtVDAC1 has a main function in mitochondria PMID:22294207
VDAC1 is not only necessary for normal growth but also important for disease resistance through regulation of hydrogen peroxide generation. PMID:21705391