VDAC1 Antibody, Biotin conjugated

Code: CSB-PA865954LD01DOA
Size:
50μl
50μl100μl
US$166
Quantity:
Species Reactivity: Arabidopsis thaliana
Raised in: Rabbit
Application: ELISA
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Product Details

Uniprot NO.
Target Names
VDAC1
Alternative Names
VDAC1 antibody; At3g01280 antibody; T22N4.9 antibody; Mitochondrial outer membrane protein porin 1 antibody; Voltage-dependent anion-selective channel protein 1 antibody; AtVDAC1 antibody; VDAC-1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana Mitochondrial outer membrane protein porin 1 protein (2-276AA)
Immunogen Species
Arabidopsis thaliana
Conjugate
Biotin
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
ELISA
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-4 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Datasheet & COA

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. Involved in plant development at reproductive stage, is important for pollen development and may regulate hydrogen peroxide generation during disease resistance.
Gene References into Functions
  1. Abnormal ovules in the process of female gametogenesis were observed. Both mitochondrial transmembrane potential and ATP synthesis rate were obviously reduced in the mitochondria isolated from atvdac1 plants. PMID:25192453
  2. Data indicate that both voltage-dependent anion channel 1 (AtVDAC1) and calcium sensor CBL1 regulate cold stress responses during seed germination and plant development. PMID:23344040
  3. AtVDAC1 has a main function in mitochondria PMID:22294207
  4. VDAC1 is not only necessary for normal growth but also important for disease resistance through regulation of hydrogen peroxide generation. PMID:21705391

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Subcellular Location
Mitochondrion outer membrane.
Protein Families
Eukaryotic mitochondrial porin (TC 1.B.8.1) family
Tissue Specificity
Expressed in shoot meristems, root meristematic zone, lateral roots, leaves, stigma and anthers.
Database Links

UNIGENE: At.24885

KEGG: ath:AT3G01280

STRING: 3702.AT3G01280.1

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