VDAC1 Antibody

CSB-PA865954LA01DOA

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20μl50μl100μl

US$83

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Species Reactivity: Arabidopsis thaliana

Raised in: Rabbit

Application: ELISA, WB

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Target Background

Product Details

Uniprot NO.

Q9SRH5

Target Names

VDAC1

Alternative Names

VDAC1 antibody; At3g01280 antibody; T22N4.9 antibody; Mitochondrial outer membrane protein porin 1 antibody; Voltage-dependent anion-selective channel protein 1 antibody; AtVDAC1 antibody; VDAC-1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana Mitochondrial outer membrane protein porin 1 protein (2-276AA)

Immunogen Species

Arabidopsis thaliana

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Protocols

ELISA Protocol Western Blotting(WB) Protocol

Datasheet & COA

Antibody FAQs

Images

Western Blot
Positive WB detected in: Arabidopsis thaliana leaf tissue, Apium graveolens leaf tissue, Spinacia oleracea leaf tissue, Glycine max leaf tissue, Capsicum annuum leaf tissue, Solanum tuberosum leaf tissue, Vicia faba leaf tissue, Ipomoea batatas leaf tissue
All lanes: VDAC1 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 30 kDa
Observed band size: 30 kDa

Description

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Target Background

Function

Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. Involved in plant development at reproductive stage, is important for pollen development and may regulate hydrogen peroxide generation during disease resistance.

Gene References into Functions

Abnormal ovules in the process of female gametogenesis were observed. Both mitochondrial transmembrane potential and ATP synthesis rate were obviously reduced in the mitochondria isolated from atvdac1 plants. PMID:25192453
Data indicate that both voltage-dependent anion channel 1 (AtVDAC1) and calcium sensor CBL1 regulate cold stress responses during seed germination and plant development. PMID:23344040
AtVDAC1 has a main function in mitochondria PMID:22294207
VDAC1 is not only necessary for normal growth but also important for disease resistance through regulation of hydrogen peroxide generation. PMID:21705391