Ifne Antibody

Code: CSB-PA800374LA01MO

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US$83

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Species Reactivity: Mouse

Raised in: Rabbit

Application: ELISA

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Target Background

Product Details

Uniprot NO.

Q80ZF2

Target Names

Ifne

Alternative Names

Ifne antibody; Ifne1 antibody; Ifnt1Interferon epsilon antibody; IFN-epsilon antibody; Interferon epsilon-1 antibody; Interferon tau-1 antibody

Raised in

Rabbit

Species Reactivity

Mouse

Immunogen

Recombinant Mouse Interferon epsilon protein (22-192AA)

Immunogen Species

Mus musculus (Mouse)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Tested Applications

ELISA

Protocols

ELISA Protocol

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Type I interferon required for maintaining basal levels of IFN-regulated genes, including 2'-5'-oligoadenylate synthetase, IRF7 and ISG15, in the female reproductive tract. Directly mediates protection against viral, including HSV-2, and bacterial, including Chlamydia muridarum, genital infections.

Gene References into Functions

IFN-epsilon is constitutively expressed by cells of the reproductive tract and is inefficiently secreted by fibroblasts and cell lines. PMID:23951133
IFN-epsilon could promote migration of antigen-specific CD8(+)T cells to the gut. PMID:22617838
Ifn-epsilon-deficient mice had increased susceptibility to infection of the female reproductive tract by the common sexually transmitted infections (STIs) herpes simplex virus 2 and Chlamydia muridarum. PMID:23449591
interactions between estradiol and IFN-tau in the context of the overall immune response during autoimmune orchitis PMID:21787220

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Subcellular Location

Secreted.

Protein Families

Alpha/beta interferon family

Tissue Specificity

Expressed at very high levels in uterus and, at much lower levels, in ovary and cervix. Very low levels, if any, in other organs. In the endometrium, expressed in the luminal and glandular epithelial cells (at protein level).

Database Links

UNIGENE: Mm.246593

KEGG: mmu:230405

STRING: 10090.ENSMUSP00000059199

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