Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
Gene References into Functions
Together, these results suggest a novel mechanism regulating PATZ1 expression based on the upregulation of miR-29b expression induced by Ras oncogene.PMID:27125250
H-ras isoform mediates protection against pressure overload-induced cardiac dysfunction in part through activation of AKT/PI3K signaling pathway.PMID:28193718
Phenotypic Screening Identifies Protein Synthesis Inhibitors as H-Ras-Nanocluster-Increasing Tumor Growth Inducers.PMID:26568031
H-Ras mediates the inhibitory effect of epidermal growth factor on the epithelial Na+ channelPMID:25774517
Data indicate that numerous proteins that are up-regulated in H-ras(G12V) transgenic rat pancreatic ductal adenocarcinoma (PDAC) are also up-regulated in human PDAC; therefore, this rat model can be used for diagnostic biomarkers for this disease.PMID:23648844
Fe(2+)-generated O(2) mediates p21(ras) and TAK1 activation via PTP inhibition and Lys(63)-polyUb of TRAF6 in caveosomes for proinflammatory M1 activation in hepatic macrophagesPMID:22829592
The proto-oncogenic H-Ras is directly involved in the promotion of muscle differentiation via PI3K and its downstream signaling pathways.PMID:20603646
Data show that Myc repressed Ras-induced senescence, and that Cdk2 interacted with Myc at promoters, where it affected Myc-dependent regulation of genes, including those of proteins known to control senescence.PMID:19966300
We examined if H-Ras and K-Ras proteins, which are distributed across different plasma membrane microdomains, have equal access to the endocytic compartment and whether this access is necessary for downstream signaling.PMID:12077341
A positive regulatory role of Ras is observed in AMPA receptor-mediated synaptic transmission in hippocampal pyramidal neurons.PMID:12824760
Functional activation of H-Ras might be one of the signaling steps involved in glucose-induced capillary cell apoptosis.PMID:14988264
Silencing of individual genes by DNA methylation is controlled by HRAS oncogenic signalling pathways, yet the mechanisms responsible for initial target gene suppression are variable.PMID:16568090
H-ras suppresses integrin affinity via independent Raf and phospholipase C epsilon signaling pathways.PMID:16895916
analysis of tumor induction with expression plasmids for activated H-ras and c-mycPMID:18218323
Infection with M. arginini made rat and mouse embryo fibroblasts susceptible to transformation with oncogenic H-RasPMID:18408766
induction of long-term potentiation triggered robust Ca2+-dependent Ras activation in single spines that decayed in approximately 5 minutes; Ras activity spread over approximately 10 micrometers of dendrite and invaded neighboring spines by diffusionPMID:18556515
trend of increased H-ras expression was observed in diabetic compared to normal rats during oncogenesisPMID:19283661