It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Tested Applications
ELISA,IHC
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA035138(Ccl6 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
CCL6(22-95) and CCL6(23-95) are potent chemoattractants.
Gene References into Functions
Mice lacking RXRalpha in myeloid cells exhibit reduced levels of CCL6 and CCL9, impaired recruitment of leukocytes to sites of inflammation, and lower susceptibility to sepsis.PMID:20498053
enhanced expression in intestinal epithelium following immunostimulation with LPS or pro-inflammatory cytokinesPMID:19812544
the injury-induced expression of C10 at the mRNA and protein levelPMID:11895334
c10 promotes fibrosis by recruiting macrophages in the inflammatory response to bleomycin in the lungPMID:12356575
CCL6 gene activation and production induced by SCF in the presence or absence of rather specific inhibitors for certain pathways demonstrated that the MEK/MAPK pathway but not the PI-3K pathway was crucial for the SCF-induced CCL6 gene activation.PMID:17234680
the chemokines CCL6 and CCL9 as genes prominently induced by the type I IFNs and ICSBPPMID:19171873
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Subcellular Location
Secreted.
Protein Families
Intercrine beta (chemokine CC) family
Tissue Specificity
Expressed in myelopoietic bone marrow cultures stimulated by GM-CSF.