Abbreviation
Recombinant Human IL13RA1 protein, partial (Active)
Purity
Greater than 95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU/ug as determined by LAL method.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human IL13RA1 at 2 μg/mL can bind Anti-IL13RA1 recombinant antibody (CSB-RA011591MA1HU). The EC50 is 0.8074-0.9029 ng/mL.
Alternative Names
Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19; CD antigen CD213a1
Species
Homo sapiens (Human)
Expression Region
22-343aa
Target Protein Sequence
GGGGAAPTETQPPVTNLSVSVENLCTVIWTWNPPEGASSNCSLWYFSHFGDKQDKKIAPETRRSIEVPLNERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCIWHNLSYMKCSWLPGRNTSPDTNYTLYYWHRSLEKIHQCENIFREGQYFGCSFDLTKVKDSSFEQHSVQIMVKDNAGKIKPSFNIVPLTSRVKPDPPHIKNLSFHNDDLYVQWENPQNFISRCLFYEVEVNNSQTETHNVFYVQEAKCENPEFERNVENTSCFMVPGVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQEMSIGKKRNST
Note: The complete
sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is
translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application,
please explicitly request the full and complete sequence of this protein before ordering.
Tag Info
C-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Buffer
Lyophilized from a 0.2 μm sterile filtered PBS, 6% Trehalose, pH 7.4
Storage
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Lead Time
3-7 business days
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Shelf Life
The shelf life is related to many factors, storage state, storage temperature and the stability of the product itself. Generally, the shelf life of lyophilized form is 6 months at -20°C/-80°C from the date of receipt.
Datasheet & COA
Please contact us to get it.
Images
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(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Activity
Measured by its binding ability in a functional ELISA. Immobilized Human IL13RA1 at 2 μg/ml can bind Anti-IL13RA1 recombinant antibody (CSB-RA011591MA1HU). The EC50 is 0.8074-0.9029 ng/mL.
Description
IL-13 receptor subunit alpha-1 mediates cellular responses to IL-13, a cytokine central to allergic inflammation and Th2-driven immune pathways, making this receptor a target for therapeutic intervention in asthma and atopic disease. This mammalian-expressed construct spanning residues 22–343 captures the extracellular ligand-binding domain with native post-translational modifications that preserve conformational epitopes, as demonstrated by functional ELISA showing dose-dependent binding to an anti-IL13RA1 recombinant antibody with an EC50 of 0.8074–0.9029 ng/mL. The quantified binding kinetics support use in competitive inhibition assays for blocking antibody screening, therapeutic antibody epitope mapping, and ligand-receptor interaction studies by ELISA, SPR, or BLI. Endotoxin levels below 1.0 EU/μg and purity exceeding 95% meet the quality thresholds commonly required for antibody validation workflows and biologic inhibitor screening in immunology research.
