TFPI

TFPI, or tissue factor pathway inhibitor, is an endogenous anticoagulant protein primarily produced in the liver, vascular endothelial cells, and macrophages. It plays a crucial role in the regulation of hemostasis by inhibiting the activity of tissue factor (TF) and factor Xa, thus maintaining the balance between blood coagulation and anticoagulation. TFPI is instrumental in preventing excessive blood coagulation, reducing thrombotic risks, and preserving vascular health. Moreover, TFPI's expression levels can be indicative of various diseases, making it a potential biomarker for research and treatment in cancer, inflammation, and cardiovascular disease.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human TFPI at 1 μg/ml can bind Anti-TFPI recombinant antibody (CSB-RA023437MA01HU), the EC₅₀ is 1.242-1.788 ng/mL.

TFPI Recombinant Monoclonal Antibody(CSB-RA023437MA01HU)

Validated Data

The Binding Activity of Human TFPI with Anti-TFPI recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human TFPI (CSB-MP023437HU) at 1 μg/mL can bind Anti-TFPI recombinant antibody, the EC₅₀ is 1.242-1.788 ng/mL.

The Binding Activity of Rabbit TFPI with Anti-TFPI recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Rabbit TFPI （CSB-MP023437RB） at 1 μg/mL can bind Anti-TFPI recombinant antibody, the EC₅₀ is 2.281-3.783 ng/mL.

The following TFPI reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TFPI Antibodies

TFPI Proteins

TFPI ELISA Kits

TFPI Antibodies

TFPI Antibodies for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Species Reactivity	Application
CSB-PA023437ZA01RB	TFPI Antibody	Oryctolagus cuniculus	ELISA, WB (ensure identification of antigen)

TFPI Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA023437GA01HU	TFPI Antibody	Human	ELISA,WB
CSB-PA005186	TFPI Antibody	Human	WB, ELISA
CSB-RA023437MA01HU	TFPI Recombinant Monoclonal Antibody	Human, Rabbit	ELISA
CSB-PA023437ZA01HU	TFPI Antibody	Homo sapiens	ELISA, WB (ensure identification of antigen)
CSB-RA023437MB1HU	TFPI (Concizumab Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA023437MB2HU	TFPI (Armocibart Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA023437MB3HU	TFPI (Concizumab-mtci Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA023437MB4HU	TFPI (Marstacimab-hncq Biosimilar) Recombinant Monoclonal Antibody	Human
CSB-RA023437MB5HU	TFPI (MG-1113 Biosimilar) Recombinant Monoclonal Antibody	Human

TFPI Proteins

TFPI Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-EP023437RB	Recombinant Rabbit Tissue factor pathway inhibitor (TFPI)	E.coli
CSB-YP023437RB	Recombinant Rabbit Tissue factor pathway inhibitor (TFPI)	Yeast
CSB-BP023437RB	Recombinant Rabbit Tissue factor pathway inhibitor (TFPI)	Baculovirus
CSB-MP023437RB	Recombinant Rabbit Tissue factor pathway inhibitor (TFPI) (Active)	Mammalian cell

TFPI Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP023437HU CSB-EP023437HU CSB-BP023437HU CSB-MP023437HU CSB-EP023437HU-B	Recombinant Human Tissue factor pathway inhibitor (TFPI), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP023437HU1	Recombinant Human Tissue factor pathway inhibitor (TFPI), partial	E.coli
CSB-MP023437HU	Recombinant Human Tissue factor pathway inhibitor (TFPI), partial (Active)	Mammalian cell

TFPI Proteins for Macaca mulatta (Rhesus macaque)

Code	Product Name	Source
CSB-YP636742MOW CSB-EP636742MOW CSB-BP636742MOW CSB-MP636742MOW CSB-EP636742MOW-B	Recombinant Macaca mulatta Tissue factor pathway inhibitor (TFPI)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP636742MOW	Recombinant Macaca mulatta Tissue factor pathway inhibitor (TFPI)	E.coli

TFPI Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP023437MO CSB-EP023437MO CSB-BP023437MO CSB-MP023437MO CSB-EP023437MO-B	Recombinant Mouse Tissue factor pathway inhibitor (Tfpi)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TFPI ELISA Kit

TFPI ELISA Kit for Rattus norvegicus (Rat)

Code	Product Name	Sample Types	Sensitivity
CSB-E08261r	Rat Tissue factor pathway inhibitor,TFPI ELISA Kit	serum, plasma, cell culture supernates, tissue homogenates	1.95 ng/mL

TFPI ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E08260h	Human Tissue factor pathway inhibitor,TFPI ELISA Kit	serum, plasma, tissue homogenates	0.293 ng/mL

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