POT1

Protection of telomeres protein 1 is a protein in humans that is encoded by POT1 gene. Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. Is a component of the double-stranded telomeric DNA-binding TRF1 complex which is involved in the regulation of telomere length by cis-inhibition of telomerase. Also acts as a single-stranded telomeric DNA-binding protein and thus may act as a downstream effector of the TRF1 complex and may transduce information about telomere maintenance and/or length to the telomere terminus. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.

The following POT1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

POT1 Antibodies

POT1 Proteins

POT1 Antibodies

POT1 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA251529XA01SVG	POT1 Antibody	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ELISA, WB (ensure identification of antigen)

POT1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA018382GA01HU	POT1 Antibody	Human,Mouse	ELISA,IHC
CSB-PA003831	POT1 Antibody	Human,Monkey	WB, ELISA
CSB-PA868326LA01HU	POT1 Antibody	Human	ELISA, IHC, IF
CSB-PA868326LB01HU	POT1 Antibody, HRP conjugated	Human	ELISA
CSB-PA868326LC01HU	POT1 Antibody, FITC conjugated	Human
CSB-PA868326LD01HU	POT1 Antibody, Biotin conjugated	Human	ELISA

POT1 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Species Reactivity	Application
CSB-PA519501XA01DOA	POT1 Antibody	Arabidopsis thaliana	ELISA, WB (ensure identification of antigen)

POT1 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA018382XA01SXV	pot1 Antibody	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ELISA, WB (ensure identification of antigen)

POT1 Proteins

POT1 Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP018382CH CSB-EP018382CH CSB-BP018382CH CSB-MP018382CH CSB-EP018382CH-B	Recombinant Chicken Protection of telomeres protein 1 (POT1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

POT1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP868326HU CSB-EP868326HU CSB-BP868326HU CSB-MP868326HU CSB-EP868326HU-B	Recombinant Human Protection of telomeres protein 1 (POT1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

POT1 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP822088MOV CSB-EP822088MOV CSB-BP822088MOV CSB-MP822088MOV CSB-EP822088MOV-B	Recombinant Macaca fascicularis Protection of telomeres protein 1 (POT1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

POT1 Proteins for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Source
CSB-YP519501DOA CSB-EP519501DOA CSB-BP519501DOA CSB-MP519501DOA CSB-EP519501DOA-B	Recombinant Arabidopsis thaliana Potassium transporter 1 (POT1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

POT1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Source
CSB-YP018382SXV CSB-EP018382SXV CSB-BP018382SXV CSB-MP018382SXV CSB-EP018382SXV-B	Recombinant Schizosaccharomyces pombe Protection of telomeres protein 1 (pot1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

POT1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP849657MO CSB-EP849657MO CSB-BP849657MO CSB-MP849657MO CSB-EP849657MO-B	Recombinant Mouse Protection of telomeres protein 1 (Pot1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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