NELFCD

NELFCD (Negative elongation factor CD) is part of the NELF protein family, which includes NELFA, NELFB, NELFE, and NELFD. The primary function of NELFCD is to negatively regulate transcription. Its structural characteristics include multiple conserved domains, such as helical structures and helix-turn-helix structures, and it forms a complex with other NELF proteins to participate in the inhibition of gene transcription. In terms of signaling pathways, NELFCD acts as a transcriptional repressor by interacting with the RNA polymerase II complex, thereby inhibiting the rate of RNA synthesis and regulating gene expression by negatively regulating gene transcription. Research on NELFCD may provide new insights for the future development of relevant drugs or therapeutic approaches.

Popular Product:

NELFCD Antibody (Code:CSB-PA815573ESR2HU)

Validated Data

WB

All lanes: NELFCD antibody at 8μg/ml
Lane 1: Jurkat whole cell lysate
Lane 2: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 67, 23, 66 kDa
Observed band size: 67 kDa

IHC

Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA815573ESR2HU at dilution of 1:100