MSH6

DNA mismatch repair protein Msh6 is a protein in humans that is encoded by MSH6 gene. Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch.

The following MSH6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

MSH6 Antibodies

MSH6 Proteins

MSH6 Antibodies

MSH6 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA280453XA01SVG	MSH6 Antibody	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ELISA, WB (ensure identification of antigen)

MSH6 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA015032GA01HU	MSH6 Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-MA0150321A0m	MSH6 Monoclonal Antibody	Human	ELISA,IHC
CSB-PA015032HA01HU	MSH6 Antibody	Human	ELISA, IHC, IF
CSB-PA015032HD01HU	MSH6 Antibody, Biotin conjugated	Human	ELISA
CSB-PA125723	MSH6 Antibody	Human,Mouse	ELISA,WB
CSB-PA002850	MSH6 Antibody	Human,Mouse,Monkey	WB, IHC, IF, ELISA
CSB-PA051370	MSH6 Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA589405	MSH6 Antibody	Human,Mouse	ELISA,WB,IHC
CSB-RA091472A0HU	MSH6 Recombinant Monoclonal Antibody	Human	ELISA, IHC, IF, FC

MSH6 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Species Reactivity	Application
CSB-PA519077XA01DOA	MSH6 Antibody	Arabidopsis thaliana	ELISA, WB (ensure identification of antigen)

MSH6 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA015032XA01SXV	msh6 Antibody	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ELISA, WB (ensure identification of antigen)

MSH6 Antibodies for Drosophila melanogaster (Fruit fly)

Code	Product Name	Species Reactivity	Application
CSB-PA894276XA01DLU	Msh6 Antibody	Drosophila melanogaster (Fruit fly)	ELISA, WB (ensure identification of antigen)

MSH6 Proteins

MSH6 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP015032HU CSB-EP015032HU CSB-BP015032HU CSB-MP015032HU CSB-EP015032HU-B	Recombinant Human DNA mismatch repair protein Msh6 (MSH6), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP015032HU	Recombinant Human DNA mismatch repair protein Msh6 (MSH6), partial	E.coli

MSH6 Proteins for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Source
CSB-YP519077DOA CSB-EP519077DOA CSB-BP519077DOA CSB-MP519077DOA CSB-EP519077DOA-B	Recombinant Arabidopsis thaliana DNA mismatch repair protein MSH6 (MSH6), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MSH6 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Source
CSB-YP015032SXV CSB-EP015032SXV CSB-BP015032SXV CSB-MP015032SXV CSB-EP015032SXV-B	Recombinant Schizosaccharomyces pombe DNA mismatch repair protein msh6 (msh6), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MSH6 Proteins for Drosophila melanogaster (Fruit fly)

Code	Product Name	Source
CSB-YP894276DLU CSB-EP894276DLU CSB-BP894276DLU CSB-MP894276DLU CSB-EP894276DLU-B	Recombinant Drosophila melanogaster Probable DNA mismatch repair protein Msh6 (Msh6), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MSH6 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP015032MO CSB-EP015032MO CSB-BP015032MO CSB-MP015032MO CSB-EP015032MO-B	Recombinant Mouse DNA mismatch repair protein Msh6 (Msh6), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MSH6 Proteins for Dictyostelium discoideum (Slime mold)

Code	Product Name	Source
CSB-YP690881DKK CSB-EP690881DKK CSB-BP690881DKK CSB-MP690881DKK CSB-EP690881DKK-B	Recombinant Dictyostelium discoideum DNA mismatch repair protein Msh6 (msh6), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Promotions

Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

Apoptosis mediated by mitochondria The Overview of Hippo Signaling Pathway The Overview of Autophagy Crosstalk Between Autophagy and Apoptosis The Overview of Wnt Signaling Pathway The Overview of Breast Cancer: Related Signaling Pathways, Therapeutic Targets The overview of TGF-β signaling pathway PI3K-Akt Signaling Pathway and Cancer Apoptosis mediated by endoplasmic reticulum Apoptosisi mediated by death receptor Aesthetic Appreciation of Apoptosis Signal Pathway An Overview of Cell Death: Necrosis and Apoptosis Do You Really Know TGF-β Superfamily?Double-Edged Sword: TGF-β The Overview of PI3-Alt Signaling Pathway How to Inquire and Utilize the Signal Pathway on KEGG LPS/TLR4 Signal Transduction Pathway Epigenetic Histone Modifications Pathway What A Paradoxical TNF Signaling Pathway-Based on Different Receptors The Overview of Fc Receptors- Classification, Related Signaling Pathways and Application