MET, also known as the hepatocyte growth factor receptor or c-Met, is the sole high-affinity receptor for hepatocyte growth factor (HGF). This receptor activates its tyrosine kinase activity upon HGF binding, which in turn stimulates cell proliferation, migration, and differentiation. MET is crucial for embryonic development, tissue regeneration, and wound healing, and it also plays a pivotal role in tumorigenesis. Abnormal MET activation has been linked to various cancers, marking it as a significant factor in oncology.
Popular
Product:
MET Recombinant Monoclonal Antibody(CSB-RA634199A0HU)
Validated Data
IHC image of CSB-RA634199A0HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
IHC image of CSB-RA634199A0HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
The following MET
reagents supplied by CUSABIO are manufactured under a
strict quality control system. Multiple applications
have been validated and solid technical support is
offered.
MET Proteins
MET Proteins for Pan troglodytes (Chimpanzee)
MET Proteins for Plectranthus scutellarioides (Coleus) (Solenostemon scutellarioides)
MET Proteins for Plecturocebus moloch (Dusky titi monkey) (Callicebus moloch)
MET Proteins for Equus caballus (Horse)
MET Proteins for Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)
MET Proteins for Eulemur macaco macaco (Black lemur)
MET Proteins for Microcebus murinus (Lesser mouse lemur) (Gray Mouse Lemur)
MET Proteins for Homo sapiens (Human)
MET Proteins for Sus scrofa (Pig)
MET Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
MET Proteins for Rhinolophus ferrumequinum (Greater horseshoe bat)
MET Proteins for Bos taurus (Bovine)
MET Proteins for Papio anubis (Olive baboon)
MET Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
MET Proteins for Callithrix jacchus (White-tufted-ear marmoset)
MET Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
MET Proteins for Gorilla gorilla gorilla (Western lowland gorilla)
MET Proteins for Ovis aries (Sheep)
MET Proteins for Echinops telfairi (Lesser hedgehog tenrec)
MET Proteins for Loxodonta africana (African elephant)
MET Proteins for Felis catus (Cat) (Felis silvestris catus)
MET Proteins for Rattus norvegicus (Rat)
MET Proteins for Mus musculus (Mouse)
