CNGB3

Cyclic nucleotide-gated cation channel beta-3 is a protein in humans that is encoded by CNGB3 gene. Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.

The following CNGB3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CNGB3 Proteins

CNGB3 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-CF850746DO	Recombinant Dog Cyclic nucleotide-gated cation channel beta-3 (CNGB3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP850746DO1 CSB-EP850746DO1 CSB-BP850746DO1 CSB-MP850746DO1 CSB-EP850746DO1-B	Recombinant Dog Cyclic nucleotide-gated cation channel beta-3 (CNGB3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CNGB3 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP885696HU CSB-EP885696HU CSB-BP885696HU CSB-MP885696HU CSB-EP885696HU-B	Recombinant Human Cyclic nucleotide-gated cation channel beta-3 (CNGB3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CNGB3 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-CF881328MO	Recombinant Mouse Cyclic nucleotide-gated cation channel beta-3 (Cngb3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP881328MO1 CSB-EP881328MO1 CSB-BP881328MO1 CSB-MP881328MO1 CSB-EP881328MO1-B	Recombinant Mouse Cyclic nucleotide-gated cation channel beta-3 (Cngb3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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