Recombinant Human Calcium homeostasis modulator protein 3 (CALHM3)

Code: CSB-CF768231HU
Size:
20μg
20μg100μg
US$5113
Quantity:
Express system: in vitro E.coli expression system
Species: Homo sapiens (Human)
Tag Info: N-terminal 10xHis-tagged
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Product Details

Target Names
CALHM3
Uniprot NO.
Species
Homo sapiens (Human)
Source
in vitro E.coli expression system
Expression Region
1-350
Target Protein Sequence
MDKFRMLFQHFQSSSESVMNGICLLLAAVTVKLYSSFDFNCPCLVHYNALYGLGLLLTPP LALFLCGLLANRQSVVMVEEWRRPAGHRRKDPGIIRYMCSSVLQRALAAPLVWILLALLD GKCFVCAFSSSVDPEKFLDFANMTPSQVQLFLAKVPCKEDELVRDSPARKAVSRYLRCLS QAIGWSVTLLLIIAAFLARCLRPCFDQTVFLQRRYWSNYVDLEQKLFDETCCEHARDFAH RCVLHFFASMRSELQARGLRRGNAGRRLELPAVPEPPAVPEPPEGLDSGSGKAHLRAISS REQVDRLLSTWYSSKPPLDLAASPGLCGGGLSHRAPTLALGTRLSQHTDV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
full length protein
Tag Info
N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Troubleshooting and FAQs
Datasheet & COA
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Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs). CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances.
Gene References into Functions
  1. This study failed to show an association between theeight SNPs of the CALHM3 genes and alzheimer disease. PMID:20164573

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Subcellular Location
Basolateral cell membrane; Multi-pass membrane protein.
Protein Families
CALHM family
Tissue Specificity
Specifically expressed in circumvallate taste bud cells.
Database Links

HGNC: 23458

UNIGENE: Hs.364624

KEGG: hsa:119395

STRING: 9606.ENSP00000358798

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