Recombinant Human Calcium homeostasis modulator protein 3 (CALHM3), partial

Product Details

Abbreviation
CALHM3
Purity
>85% (SDS-PAGE)
Target Names
CALHM3
Uniprot NO.
Species
Homo sapiens (Human)
Source
Yeast
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs). CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances.
Gene References into Functions
  1. This study failed to show an association between theeight SNPs of the CALHM3 genes and alzheimer disease. PMID:20164573

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Subcellular Location
Basolateral cell membrane; Multi-pass membrane protein.
Protein Families
CALHM family
Tissue Specificity
Specifically expressed in circumvallate taste bud cells.
Database Links

HGNC: 23458

UNIGENE: Hs.364624

KEGG: hsa:119395

STRING: 9606.ENSP00000358798

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