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Recombinant Simian immunodeficiency virus agm.grivet Gag polyprotein (gag)

Recombinant Simian immunodeficiency virus agm.grivet Gag polyprotein (gag)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

gag

Uniprot NO.

Q02843

Species

Simian immunodeficiency virus agm.grivet (isolate AGM gr-1) (SIV-agm.gri) (Simian immunodeficiency virus African green monkey grivet)

Source

Yeast

Expression Region

2-513

Target Protein Sequence

GGGHSALSG RSLDTFEKIR LRPNGKKKYQ IKHLIWAGKE MERFGLHEKL LETKEGCQKI IEVLTPLEPT GSEGLKALFN LCCVIWCIHA EQKVKDTEEA VVTVKQHYHL VDKNEKAAKK KNETTAPPGG ESRNYPVVNQ NNAWVHQPLS PRTLNAWVKC VEEKRWGAEV VPMFQALSEG CLSYDVNQML NVIGDHQGAL QILKEVINEE AAEWDRTHRP PAGPLPAGQL RDPTGSDIAG TTSSIQEQIE WTFNANPRID VGAQYRKWVI LGLQKVVQMY NPQKVLDIRQ GPKEPFQDYV DRFYKALRAE QAPQDVKNWM TQTLLIQNAN PDCKLILKGL GMNPTLEEML IACQGVGGPQ HKAKLMVEMM SNGQNMVQVG PQKKGPRGPL KCFNCGKFGH MQRECKAPRQ IKCFKCGKIG HMAKDCKNGQ ANFLGYGHWG GAKPRNFVQY RGDTVGLEPT APPMETAYDP AKKLLQQYAE KGQRLREERE QTRKQKEKEV EDVSLSSLFG GDQ
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Matrix protein p17 targets Gag and Gag-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex. Implicated in the release from host cell mediated by Vpu.; Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.; Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers.; p6-gag plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.

Gene References into Functions

results indicate that certain residues in the capsid N terminus are crucial for early budding events PMID:15866069
NMR structure of SIV NCp8 compared with that of HIV NCp7 PMID:16229684
identifid an N-terminally truncated SIV Pr55(Gag) isoform expressed from the SIV gag gene SIV p43; translation of SIV p43 is driven by an IRES located entirely within the coding region of gag mRNA PMID:16494914

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Subcellular Location

[Matrix protein p17]: Virion. Host nucleus. Host cytoplasm. Host cell membrane; Lipid-anchor.; [Capsid protein p24]: Virion.; [Nucleocapsid protein p7]: Virion.

Protein Families

Primate lentivirus group gag polyprotein family

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