Made-to-order (14-16 weeks)
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Value-added Deliverables
① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive;
Matrix protein p17 targets Gag and Gag-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex. Implicated in the release from host cell mediated by Vpu.; Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.; Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers.; p6-gag plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
Gene References into Functions
results indicate that certain residues in the capsid N terminus are crucial for early budding eventsPMID:15866069
NMR structure of SIV NCp8 compared with that of HIV NCp7PMID:16229684
identifid an N-terminally truncated SIV Pr55(Gag) isoform expressed from the SIV gag gene SIV p43; translation of SIV p43 is driven by an IRES located entirely within the coding region of gag mRNAPMID:16494914
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Subcellular Location
[Matrix protein p17]: Virion. Host nucleus. Host cytoplasm. Host cell membrane; Lipid-anchor.; [Capsid protein p24]: Virion.; [Nucleocapsid protein p7]: Virion.