Recombinant Rat Tonin (Klk2)

Code: CSB-YP012453RA
Size:
20ug
20ug100ug1mg
US$368
Quantity:
Express system: Yeast
Species: Rattus norvegicus (Rat)
Tag Info: C-terminal 6xHis-tagged
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Product Details

Abbreviation
Recombinant Rat Klk2 protein
Purity
Greater than 95% as determined by SDS-PAGE.
Target Names
Klk2
Uniprot NO.
Research Area
Cancer
Alternative Names
Esterase 1;Glandular kallikrein-2;RSKG-5;S2 kallikrein
Species
Rattus norvegicus (Rat)
Source
Yeast
Expression Region
25-259aa
Target Protein Sequence
IVGGYKCEKNSQPWQVAVINEYLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNLFKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLPTKEPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLCAGEMEGGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Mol. Weight
26.9 kDa
Protein Length
Full Length of Mature Protein
Tag Info
C-terminal 6xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.264.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Troubleshooting and FAQs
Datasheet & COA
Please contact us to get it.
Images
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
This protein has both trypsin- and chymotrypsin-like activities, being able to release angiotensin II from angiotensin I or angiotensinogen.
Gene References into Functions
  1. the environment of tonin abundance may increase N-domain ACE activity liberated by a secretase able to cleave somatic ACE. PMID:26216430
  2. Tonin in the brain may represent an alternative pathway for angiotensin II generation with effects on the cardiovascular system. PMID:20180641
  3. expression in the rat brain and mediation of the central production of angiotensin II PMID:12044607
  4. tonin may play a role in the process of heart hypertrophy PMID:12543632
  5. KLK2 rat gene was expressed at high levels in the submandibular glands of transgenic mice. PMID:17366701

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Protein Families
Peptidase S1 family, Kallikrein subfamily
Tissue Specificity
Found in submaxillary gland.
Database Links

UNIGENE: Rn.9882

KEGG: rno:24841

STRING: 10116.ENSRNOP00000025701

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