Recombinant Rat Thyrotropin subunit beta (Tshb)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Tshb

Uniprot NO.

P04652

Species

Rattus norvegicus (Rat)

Source

Mammalian cell

Expression Region

21-132

Target Protein Sequence

FCIPTEYMMY VDRRECAYCL TINTTICAGY CMTRDINGKL FLPKYALSQD VCTYRDFTYR TVEIPGCPHH VAPYFSYPVA LSCKCGKCNT DYSDCTHEAV KTNYCTKPQT FY
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Indispensable for the control of thyroid structure and metabolism.

Gene References into Functions

These data add new insight to an important role of T3 in rapidly regulating TSH beta gene expression at posttranscriptional level. PMID:21078364
TSH action stimulates the phosphorylation of hsp-90 in FRTL-5 thyroid cells PMID:16910874
Results clearly show that there are diurnal changes in TSH expression and accumulation in rat PT-TSH cells and suggest that these fluctuations are regulated by melatonin. PMID:17927662

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Subcellular Location

Secreted.

Protein Families

Glycoprotein hormones subunit beta family

Database Links

UNIGENE: Rn.9966

KEGG: rno:25653

STRING: 10116.ENSRNOP00000022575

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