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Recombinant Rat Interleukin-2 receptor subunit alpha (Il2ra), partial

Recombinant Rat Interleukin-2 receptor subunit alpha (Il2ra), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Il2ra

Uniprot NO.

P26897

Species

Rattus norvegicus (Rat)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

Gene References into Functions

Adoptive transfusion of CD4+CD25+ (Interleukin-2 Receptor alpha) Regulatory T Cells into Experimental Autoimmune Neuritis model rats has significant therapeutic effects. PMID:29772575
Deletion of antigen-specific T cells by apoptosis and active suppression mediated by CD4(+)CD25(+) T-regulatory cells has an important role in the induction of antigen specific immune tolerance PMID:19884905

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Subcellular Location

Membrane; Single-pass type I membrane protein.

Database Links

UNIGENE: Rn.9872

KEGG: rno:25704

STRING: 10116.ENSRNOP00000066383

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