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Recombinant Rat C3a anaphylatoxin chemotactic receptor (C3ar1), partial

Recombinant Rat C3a anaphylatoxin chemotactic receptor (C3ar1), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

C3ar1

Uniprot NO.

O55197

Alternative Names

C3ar1; C3a anaphylatoxin chemotactic receptor; C3AR; C3a-R

Species

Rattus norvegicus (Rat)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

Gene References into Functions

C5aR and C5L2, but not C3aR, are expressed on CD11b-positive leukocytes in islet preparations PMID:22099750
The C3 and C3a receptor system may primarily be involved in the pathogenesis of renal remodeling in hypertensive rats. PMID:23713944
The binding of TLQP-21 to C3AR1 not only has effects on signaling but also modulates cellular functions PMID:23940034
results provide the first evidence that C3aR and C5aR are both expressed in cerebellar granule cells during development and that C5a, but not C3a, is a potent inhibitor of apoptotic cell death in cultured granule neurons PMID:15292245
Role of C3ar1 in the development of the rat cerebellum is reported. PMID:18635264