Recombinant Rat C-X-C motif chemokine 3 (Cxcl3)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

Cxcl3

Purity

>85% (SDS-PAGE)

Target Names

Cxcl3

Uniprot NO.

Q10746

Alternative Names

Cxcl3; Cinc2C-X-C motif chemokine 3; Cytokine-induced neutrophil chemoattractant 2; CINC-2; Macrophage inflammatory protein 2-alpha/beta; MIP2-alpha/beta

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

33-101

Target Protein Sequence

RELRCQCL KTLPRVDFEN IQSLTVTPPG PHCTQTEVIA TLKDGQEVCL NPQAPRLQKI IQKLLKSDKS S
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.

Gene References into Functions

this study shows elevated expression of CINC-2 at the site of inflammation as well as their significant reflection in the circulation, thereby suggesting their frontline role in carrageenan-induced acute inflammation PMID:27967265
CINC-2beta is regulated differently from most other chemokines and that its expression is related to the state of alveolar type II cell differentiation. PMID:16055671

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Subcellular Location

Secreted.

Protein Families

Intercrine alpha (chemokine CxC) family

Database Links

UNIGENE: Rn.10525

KEGG: rno:171551

STRING: 10116.ENSRNOP00000038520

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