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Recombinant Papio hamadryas Androgen receptor (AR), partial

Recombinant Papio hamadryas Androgen receptor (AR), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Uniprot NO.

O97960

Alternative Names

AR; NR3C4Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4

Species

Papio hamadryas (Hamadryas baboon)

Source

Yeast

Expression Region

1-895

Target Protein Sequence

MEVQLGLGRV YPRPPSKTYR GAFQNLFQSV REVIQNPGPR HPEAASAAPP GASLQQQQQQ QQQETSPRQQ QQQQGEDGSP QAHRRGPTGY LVLDEEQQPS QPQSAPECHP ERGCVPEPGA AVAAGKGLPQ QLPAPPDEDD SAAPSTLSLL GPTFPGLSSC SADLKDILSE ASTMQLLQQQ QQEAVSEGSS SGRAREASGA PTSSKDNYLG GTSTISDSAK ELCKAVSVSM GLGVEALEHL SPGEQLRGDC MYAPVLGVPP AVRPTPCAPL AECKGSLLDD SAGKSTEDTA EYSPFKGGYT KGLEGESLGC SGSAAAGSSG TLELPSTLSL YKSGALDEAA AYQSRDYYNF PLALAGPPPP PPPPHPHARI KLENPLDYGS AWAAAAAQCR YGELASLHGA GAAGPGSGSP SAAASSSWHT LFTAEEGQLY GPCGGGGGGG GGGGGGAGEA GAVAPYGYTR PPQGLAGQEG DFTAPDVWYP GGMVSRVPYP SPTCVKSEMG PWMDSYSGPY GDMRLETARD HVLPIDYYFP PQKTCLICGD EASGCHYGAL TCGSCKVFFK RAAEGKQKYL CASRNDCTID KFRRKNCPSC RLRKCYEAGM TLGARKLKKL GNLKLQEEGE ASSTTSPTEE TAQKLTVSHI EGYECQPIFL NVLEAIEPGV VCAGHDNNQP DSFAALLSSL NELGERQLVH VVKWAKALPG FRNLHVDDQM AVIQYSWMGL MVFAMGWRSF TNVNSRMLYF APDLVFNEYR MHKSRMYSQC VRMRHLSQEF GWLQITPQEF LCMKALLLFS IIPVDGLKNQ KFFDELRMNY IKELDRIIAC KRKNPTSCSR RFYQLTKLLD SVQPIARELH QFTFDLLIKS HMVSVDFPEM MAEIISVQVP KILSGKVKPI YFHTQ
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.

Subcellular Location

Nucleus. Cytoplasm.

Protein Families

Nuclear hormone receptor family, NR3 subfamily

Recombinant Papio hamadryas Androgen receptor (AR), partial

Product Details

Related Products

Customer Reviews and Q&A

Target Background