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Recombinant Mouse Thyroid peroxidase (Tpo), partial

Recombinant Mouse Thyroid peroxidase (Tpo), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details

Purity

>85% (SDS-PAGE)

Target Names

Tpo

Uniprot NO.

P35419

Alternative Names

Tpo; Thyroid peroxidase; TPO; EC 1.11.1.8

Species

Mus musculus (Mouse)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).

Gene References into Functions

Lnk Deficiency Leads to TPO-Mediated Osteoclastogenesis and Increased Bone Mass Phenotype PMID:28067429
Hearing impairment in hypothyroid dwarf mice caused by mutations of the thyroid peroxidase gene. PMID:24297261
A novel hypothyroid dwarfism is due to the missense mutation Arg479Cys of the thyroid peroxidase gene in the mouse. PMID:16762971

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Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Families

Peroxidase family, XPO subfamily

Database Links

UNIGENE: Mm.4991

KEGG: mmu:22018

STRING: 10090.ENSMUSP00000021005

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