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Recombinant Mouse Leukocyte antigen CD37 (Cd37), partial

Recombinant Mouse Leukocyte antigen CD37 (Cd37), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

Cd37

Purity

>85% (SDS-PAGE)

Target Names

Cd37

Uniprot NO.

Q61470

Species

Mus musculus (Mouse)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Gene References into Functions

CD37 may protect against IgA nephropathy by inhibition of the IL-6 pathway. PMID:29551516
this study identifies CD37 as a tumor suppressor that directly protects against B cell lymphomagenesis PMID:26784544
The CD37-targeted antibody-drug conjugate IMGN529 is highly active against human CLL and in a novel CD37 transgenic murine leukemia model. PMID:24445867
The cellular defect that underlies poor cellular immune induction in CD37-defcient mice is impaired dendritic cell migration. PMID:23420539
CD37 was required for the mobility and clustering of alpha(4)beta(1) integrins in the plasma membrane, thus regulating the membrane distribution of alpha(4)beta(1) integrin necessary for activation of the Akt survival pathway PMID:23150881
CD37 protects against glomerular IgA deposition and renal pathology PMID:20348240
The influence of CD37 in the early events of T cell receptor signaling demonstrates a regulatory role for CD37 in T cell proliferation. PMID:14978098
tetraspanin protein CD37 inhibits IgA responses and regulates the anti-fungal immune response. PMID:19282981