Recombinant Mouse Glycophorin-A (Gypa), partial

Product Details

Purity
>85% (SDS-PAGE)
Target Names
Gypa
Uniprot NO.
Alternative Names
Gypa; Glycophorin-A; CD antigen CD235a
Species
Mus musculus (Mouse)
Source
Yeast
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Glycophorin A is the major intrinsic membrane sialoglycoprotein of the erythrocyte. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane.
Gene References into Functions
  1. Data suggest that glycophorin A (Gpa) increases expression and activity of Cl-/HCO3- exchanger Ae1, that G719D mutation renders Ae1 mutant constructs GPA-unresponsive, and suggests a role for Ae1 amino acids 22-28 in GPA responsiveness. PMID:21455273
  2. Glycophorin A has an essential role in the expression of O-linked antigens on the erythrocyte membrane. PMID:12940824
  3. SCL is a nucleation factor within a higher-order complex required to activate glycophorin A expression PMID:14749362
  4. The resistance of glycophorin A knockout mice against infection with the OB1 variant of Babesia rohaini may be attributed to the effective clearance of the parasitized erythrocytes lacking GPA in the spleen. PMID:19084340

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Subcellular Location
Membrane; Single-pass type III membrane protein.
Protein Families
Glycophorin-A family
Database Links
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