Recombinant Mouse G-protein coupled receptor family C group 5 member B (Gprc5b), partial

Product Details

Abbreviation
Gprc5b
Purity
>85% (SDS-PAGE)
Target Names
Gprc5b
Uniprot NO.
Alternative Names
Gprc5b; Raig2; G-protein coupled receptor family C group 5 member B; Retinoic acid-induced gene 2 protein; RAIG-2
Species
Mus musculus (Mouse)
Source
Yeast
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
Gene References into Functions
  1. In Gprc5b(-/-) mice, long-term motor learning was impaired in both the rotarod test and the horizontal optokinetic response eye movement (HOKR) test PMID:29481883
  2. The G protein-coupled receptor GPRC5B contributes to neurogenesis in the developing mouse neocortex. PMID:24089469
  3. GPRC5B activates obesity-associated inflammatory signaling in adipocytes. PMID:23169819
  4. GPRC5B has important roles for animal behavior controlled by the central nervous system. PMID:21840300
  5. Gprc5b-v2 may play a role during brain maturation and in matured brain, possibly through the regulation of neuronal morphology and protein-protein interaction PMID:20436672
  6. GPRC5B is involved in retinoic acid -dependent morphogenesis/angiogenesis and regulation of extracellular matrix synthesis in the murine placenta and yolk sac. PMID:17652913

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Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 3 family
Database Links

UNIGENE: Mm.103439

KEGG: mmu:64297

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