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Recombinant Severe acute respiratory syndrome coronavirus ORF3a protein (3a), partial

Recombinant Severe acute respiratory syndrome coronavirus ORF3a protein (3a), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details

Purity

>85% (SDS-PAGE)

Target Names

Uniprot NO.

P59632

Alternative Names

3a; ORF3a protein; Accessory protein 3a; Protein 3a; Protein U274; Protein X1

Species

Human SARS coronavirus (SARS-CoV) (Severe acute respiratory syndrome coronavirus)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Forms homotetrameric potassium sensitive ion channels (viroporin) and may modulate virus release. Up-regulates expression of fibrinogen subunits FGA, FGB and FGG in host lung epithelial cells. Induces apoptosis in cell culture. Downregulates the type 1 interferon receptor by inducing serine phosphorylation within the IFN alpha-receptor subunit 1 (IFNAR1) degradation motif and increasing IFNAR1 ubiquitination.

Subcellular Location

Virion. Host Golgi apparatus membrane; Multi-pass membrane protein. Host cell membrane; Multi-pass membrane protein. Secreted. Host cytoplasm. Note=The cell surface expressed protein can undergo endocytosis. The protein is secreted in association with membranous structures.

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Recombinant Severe acute respiratory syndrome coronavirus ORF3a protein (3a), partial

Product Details

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Customer Reviews and Q&A

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