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Recombinant Human Probable G-protein coupled receptor 179 (GPR179), partial

Recombinant Human Probable G-protein coupled receptor 179 (GPR179), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details

Abbreviation

GPR179

Purity

>85% (SDS-PAGE)

Target Names

GPR179

Uniprot NO.

Q6PRD1

Species

Homo sapiens (Human)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Orphan receptor, involved in vision. Required for signal transduction through retinal depolarizing bipolar cells.

Gene References into Functions

In this study, a novel compound heterozygous mutation, c.[1A>G]; [608G>T] (p.[0?]; p.[W203L]), was identified in the LRIT3 gene of a proband. No mutations were identified in the CABP4 or GPR179 gene. PMID:27428514
We found 1 mutation in GPR179 in congenital stationary night blindness. PMID:23714322
Additional screening with Sanger sequencing of 40 patients identified three other cCSNB patients harboring additional allelic mutations in GPR179. PMID:22325361

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Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 3 family

Tissue Specificity

Expressed in the retina.

Database Links

HGNC: 31371

UNIGENE: Hs.462915

KEGG: hsa:440435

STRING: 9606.ENSP00000345060