GPR179 Antibody, Biotin conjugated

Code: CSB-PA757664LD01HU

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Size:

50μg100μg

US$166

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Species Reactivity: Human

Raised in: Rabbit

Application: ELISA

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Target Background

Product Details

Uniprot NO.

Q6PRD1

Target Names

GPR179

Alternative Names

G protein coupled receptor 179 antibody; GP179_HUMAN antibody; GPR158 like 1 antibody; GPR158L1 antibody; GPR179 antibody; Probable G-protein coupled receptor 158-like 1 antibody; Probable G-protein coupled receptor 179 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Probable G-protein coupled receptor 179 protein (1440-1671AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Tested Applications

ELISA

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Orphan receptor, involved in vision. Required for signal transduction through retinal depolarizing bipolar cells.

Gene References into Functions

In this study, a novel compound heterozygous mutation, c.[1A>G]; [608G>T] (p.[0?]; p.[W203L]), was identified in the LRIT3 gene of a proband. No mutations were identified in the CABP4 or GPR179 gene. PMID:27428514
We found 1 mutation in GPR179 in congenital stationary night blindness. PMID:23714322
Additional screening with Sanger sequencing of 40 patients identified three other cCSNB patients harboring additional allelic mutations in GPR179. PMID:22325361

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Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 3 family

Tissue Specificity

Expressed in the retina.

Database Links

HGNC: 31371

UNIGENE: Hs.462915

KEGG: hsa:440435

STRING: 9606.ENSP00000345060