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Recombinant Human Probable G-protein coupled receptor 158 (GPR158), partial

Recombinant Human Probable G-protein coupled receptor 158 (GPR158), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

GPR158

Purity

>85% (SDS-PAGE)

Target Names

GPR158

Uniprot NO.

Q5T848

Species

Homo sapiens (Human)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Orphan receptor.

Gene References into Functions

Our results suggest that common ethnic-specific variation in GPR158 may influence energy expenditure (EE) in Pima Indians. rs11014566 nominally associated with measures of EE and adiposity, where the G allele associated with lower 24-h EE, lower Resting Metabolic Rate, higher BMI, and higher percent body fat. But, the association of rs11014566 with BMI did not directionally replicate when assessed in other ethnic groups. PMID:28476931
expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression PMID:25693195
Mutation of the NLS abrogates GPR158-mediated enhancement of cell proliferation. PMID:23451275

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Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 3 family

Database Links

HGNC: 23689

UNIGENE: Hs.499108

KEGG: hsa:57512

STRING: 9606.ENSP00000365529

OMIM: 614573

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