GPR158 Antibody, Biotin conjugated

Code: CSB-PA735975LD01HU

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Size:

50μg100μg

US$166

Quantity:

Species Reactivity: Human

Raised in: Rabbit

Application: ELISA

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Target Background

Product Details

Uniprot NO.

Q5T848

Target Names

GPR158

Alternative Names

5330427M13Rik antibody; GP158_HUMAN antibody; GPR158 antibody; mKIAA1136 antibody; Probable G-protein coupled receptor 158 antibody; RP11-59G22.1 antibody; RP23-133B16.1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Probable G-protein coupled receptor 158 protein (882-1003AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Tested Applications

ELISA

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Datasheet & COA

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Target Background

Function(From Uniprot)

Orphan receptor.

Gene References into Functions

Our results suggest that common ethnic-specific variation in GPR158 may influence energy expenditure (EE) in Pima Indians. rs11014566 nominally associated with measures of EE and adiposity, where the G allele associated with lower 24-h EE, lower Resting Metabolic Rate, higher BMI, and higher percent body fat. But, the association of rs11014566 with BMI did not directionally replicate when assessed in other ethnic groups. PMID:28476931
expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression PMID:25693195
Mutation of the NLS abrogates GPR158-mediated enhancement of cell proliferation. PMID:23451275

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Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 3 family

Database Links

HGNC: 23689

UNIGENE: Hs.499108

KEGG: hsa:57512

STRING: 9606.ENSP00000365529

OMIM: 614573

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