Home
Product
Protein
Recombinant Proteins
Recombinant Human Mas-related G-protein coupled receptor member X3 (MRGPRX3), partial

Recombinant Human Mas-related G-protein coupled receptor member X3 (MRGPRX3), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Abbreviation

MRGPRX3

Purity

>85% (SDS-PAGE)

Target Names

MRGPRX3

Uniprot NO.

Q96LB0

Species

Homo sapiens (Human)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins.

Gene References into Functions

Our data demonstrate that GPR182 is an endothelial subtype-specific marker for human sinusoidal EC of the liver, spleen, lymph node and bone marrow. In addition, we provide evidence for GPR182-dependent downstream signaling via ERK and SRF pathways that may be involved in regulating endothelial subtype-specific sinusoidal differentiation and sinusoidal functions such as permeability. PMID:29408502
Potential of GPCRs to modulate MAPK and mTOR pathways in different stages of the neurodegenerative disease. PMID:28189739
overexpression of the human MrgX3 gene causes a disturbance of the normal cell-differentiation process PMID:15809047

Hide All

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 1 family, Mas subfamily

Tissue Specificity

Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.

Database Links

HGNC: 17980

UNIGENE: Hs.380177

KEGG: hsa:117195

STRING: 9606.ENSP00000379571