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Recombinant Human Guanine nucleotide-binding protein G (s) subunit alpha isoforms short

Recombinant Human Guanine nucleotide-binding protein G (s) subunit alpha isoforms short

Baculovirus
Mammalian cell

Code
MSDS	MSDS
Size	Pls inquire
Source
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

GNAS

Uniprot NO.

P63092

Species

Homo sapiens (Human)

Source

Yeast

Expression Region

1-394

Target Protein Sequence

MGCLGNSKTE DQRNEEKAQR EANKKIEKQL QKDKQVYRAT HRLLLLGAGE SGKSTIVKQM RILHVNGFNG EGGEEDPQAA RSNSDGEKAT KVQDIKNNLK EAIETIVAAM SNLVPPVELA NPENQFRVDY ILSVMNVPDF DFPPEFYEHA KALWEDEGVR ACYERSNEYQ LIDCAQYFLD KIDVIKQADY VPSDQDLLRC RVLTSGIFET KFQVDKVNFH MFDVGGQRDE RRKWIQCFND VTAIIFVVAS SSYNMVIRED NQTNRLQEAL NLFKSIWNNR WLRTISVILF LNKQDLLAEK VLAGKSKIED YFPEFARYTT PEDATPEPGE DPRVTRAKYF IRDEFLRIST ASGDGRHYCY PHFTCAVDTE NIRRVFNDCR DIIQRMHLRQ YELL

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Description

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Target Background

Function

Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.

Subcellular Location

Cell membrane; Lipid-anchor.

Protein Families

G-alpha family, G(s) subfamily

Database Links

HGNC: 4392

UNIGENE: Hs.125898

KEGG: hsa:2778

OMIM: 103580