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Recombinant Human Glycylpeptide N-tetradecanoyltransferase 2 (NMT2)

Recombinant Human Glycylpeptide N-tetradecanoyltransferase 2 (NMT2)

Baculovirus
Mammalian cell

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

NMT2

Uniprot NO.

O60551

Alternative Names

EC 2.3.1.97; Glycylpeptide N tetradecanoyltransferase 2; Glycylpeptide N-tetradecanoyltransferase 2; Myristoyl CoA:protein N myristoyltransferase 2; Myristoyl-CoA:protein N-myristoyltransferase 2; N-myristoyltransferase 2; NMT 2; NMT2; NMT2_HUMAN; Peptide N myristoyltransferase 2; Peptide N-myristoyltransferase 2; Type II N myristoyltransferase ; Type II N-myristoyltransferase

Species

Homo sapiens (Human)

Source

Yeast

Expression Region

1-498

Target Protein Sequence

MAEDSESAAS QQSLELDDQD TCGIDGDNEE ETEHAKGSPG GYLGAKKKKK KQKRKKEKPN SGGTKSDSAS DSQEIKIQQP SKNPSVPMQK LQDIQRAMEL LSACQGPARN IDEAAKHRYQ FWDTQPVPKL DEVITSHGAI EPDKDNVRQE PYSLPQGFMW DTLDLSDAEV LKELYTLLNE NYVEDDDNMF RFDYSPEFLL WALRPPGWLL QWHCGVRVSS NKKLVGFISA IPANIRIYDS VKKMVEINFL CVHKKLRSKR VAPVLIREIT RRVNLEGIFQ AVYTAGVVLP KPIATCRYWH RSLNPRKLVE VKFSHLSRNM TLQRTMKLYR LPDVTKTSGL RPMEPKDIKS VRELINTYLK QFHLAPVMDE EEVAHWFLPR EHIIDTFVVE SPNGKLTDFL SFYTLPSTVM HHPAHKSLKA AYSFYNIHTE TPLLDLMSDA LILAKSKGFD VFNALDLMEN KTFLEKLKFG IGDGNLQYYL YNWRCPGTDS EKVGLVLQ
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.

Gene References into Functions

ligand binding properties of the NMT/ACBD6 complex can explain how the NMT reaction can proceed in the presence of the very abundant competitive substrate, C(16)-CoA. PMID:26621918
induction of NMT2 may play a central role in dioxin carcinogenicity. PMID:11731439
NMT1 and NMT2 have only partially overlapping functions; NMT1 is critical for tumor cell proliferation PMID:16123142
Involved in progression and regulation of telomerase PMID:16364039
Protein-protein interaction of NMTs revealed that m-calpain interacts with NMT1 while caspase-3 interacts with NMT2. PMID:16530191
Disruption of the gene for NMT2 by a t(8;10) translocation in a male with hypogonadism. PMID:17568424
Nef is preferentially myristoylated by NMT2, suggesting that selective inhibition of NMT2 may provide a novel means of blocking HIV virulence. PMID:18089753