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Recombinant Human Glutamate [NMDA] receptor subunit 3B (GRIN3B), partial

Recombinant Human Glutamate [NMDA] receptor subunit 3B (GRIN3B), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

GRIN3B

Uniprot NO.

O60391

Alternative Names

GluN3B; Glutamate [NMDA] receptor subunit 3B; Glutamate receptor ionotropic N methyl D aspartate 3B ; Glutamate receptor ionotropic NMDA 3B; GRIN3B; N-methyl-D-aspartate receptor subtype 3B; NMD3B_HUMAN; NMDA receptor subunit 3B; NMDA type glutamate receptor subunit NR3B; NMDAR3B; NR3B

Species

Homo sapiens (Human)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine.

Gene References into Functions

GRIN3B missense mutation is an inherited risk factor for schizophrenia. PMID:28132660
Authors investigated the significance of a common human genetic variation of the NMDAR NR3B subunit PMID:25768306
Rs2240158 of GRIN3B was significantly associated with mismatch negativity in healthy subjects. PMID:24814139
our findings suggest that the over-expression of NR3B subunit of NMDA receptor is a long lasting result of chronic opioid abuse. PMID:20153313
These observations suggest that the genetic variation of the NR3B subunit of the NMDA receptor is not a risk factor for Alzheimer's dis pathogenesis PMID:20016182
NR3B mRNA expression in the human hippocampal formation (CA1-CA4 and dentate gyrus) and adjacent neocortex may have implications for understanding the role of NMDA receptors for physiological and pathological processes in these forebrain regions. PMID:15722182
cross-talk between NR3B and NR4A receptors is a mechanism modulating the transcriptional activities of these orphan nuclear receptors PMID:17543277
We tested whether genetic dysfunction of GRIN3B is implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS). PMID:17687115